Nup210 | nucleoporin 210
Physiological systems
20 / 24 physiological systems tested
2 Significantly impacted by the knock-out
Vision/eye Liver/biliary system
18 No significant impact
4 Not tested
Data collections
Gene metrics:4Significant phenotypes
0Associated diseases
Expression examined in:0Adult tissues
0Embryo tissues
| abnormal vitreous body morphology | 1 supporting dataset | Nup210em1(IMPC)Mbp | homozygote | Early adult | 4.57x10-5 | ||
| small liver | 1 supporting dataset | Nup210em1(IMPC)Mbp | homozygote | Early adult | N/A * | ||
| abnormal liver morphology | 1 supporting dataset | Nup210em1(IMPC)Mbp | homozygote | Early adult | N/A * | ||
| cataract | 1 supporting dataset | Nup210em1(IMPC)Mbp | homozygote | Early adult | 6.35x10-5 |
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Human diseases caused by Nup210 mutations
The analysis uses data from IMPC, along with published data on other mouse mutants, in comparison to human disease reports in OMIM, Orphanet, and DECIPHER.
Phenotype comparisons summarize the similarity of mouse phenotypes with human disease phenotypes.
External links
No external links available for Nup210.
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| Nup210em1(IMPC)Mbp | Exon Deletion | | mouse |
| Nup210tm1a(EUCOMM)Hmgu | KO first allele (reporter-tagged insertion with conditional potential) | | targeting vector ES Cell |
| Nup210tm1e(EUCOMM)Hmgu | Targeted, non-conditional allele | | ES Cell |