Dnal4 | dynein, axonemal, light chain 4

GeneMGI:1859217Synonyms: Dnalc4, D15Ertd424e

Physiological systems

18 / 24 physiological systems tested

2 Significantly impacted by the knock-out

Behavior/neurological Mortality/aging

16 No significant impact

6 Not tested

Data collections

LacZ expression
Histopathology
Images
How IMPC generates data

Viability data
Body weight measurements
Embryo imaging data

Allele products available

Gene metrics:3Significant phenotypes

2Associated diseases

Expression examined in:0Adult tissues

0Embryo tissues

Phenotypes

Zygosity:

Phy. System:



preweaning lethality, incomplete penetrance	1 supporting dataset	Dnal4^{tm1b(EUCOMM)Wtsi}	homozygote	Early adult	N/A ^*
decreased exploration in new environment	1 supporting dataset	Dnal4^{tm1b(EUCOMM)Wtsi}	heterozygote	Early adult	9.6x10^-7
tremors	1 supporting dataset	Dnal4^{tm1b(EUCOMM)Wtsi}	heterozygote	Early adult	7.93x10^-5

* Does not have a P-value assigned because it was manually marked as significant.

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* This parameter was manually assessed for significance.

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lacZ Expression

No adult expression data available for Dnal4.

Associated images

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Histopathology

There is no histopathology data found for Dnal4.

IMPC related publications

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External links

No external links available for Dnal4.

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*Dnal4^{tm1a(EUCOMM)Wtsi}*	KO first allele (reporter-tagged insertion with conditional potential)	‌	targeting vector ES Cell mouse
*Dnal4^{tm1b(EUCOMM)Wtsi}*	Reporter-tagged deletion allele (with selection cassette)	‌	mouse
*Dnal4^{tm1e(EUCOMM)Hmgu}*	Targeted, non-conditional allele	‌	ES Cell
*Dnal4^{tm1e(EUCOMM)Wtsi}*	Targeted, non-conditional allele	‌	ES Cell

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