Ddah2 | DDAH family member 2, ADMA independent

GeneMGI:1859016Synonyms: G6a, Ddah, +2 more

Physiological systems

1 / 24 physiological systems tested

1 Significantly impacted by the knock-out

 Mortality/aging

23 Not tested

Data collections

LacZ expression
Histopathology
Images
How IMPC generates data
Viability data
Body weight measurements
Embryo imaging data
Gene metrics:2Significant phenotypes
0Associated diseases
Expression examined in:0Adult tissues
0Embryo tissues

Phenotypes

preweaning lethality, complete penetrance3 supporting datasetsDdah2tm1.1(KOMP)VlcghomozygoteEarly adultN/A * 
preweaning lethality, incomplete penetrance1 supporting datasetDdah2tm1.1(KOMP)VlcgheterozygoteEarly adultN/A * 
* Does not have a P-value assigned because it was manually marked as significant.
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* This parameter was manually assessed for significance.
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lacZ Expression

Associated images

Human diseases caused by Ddah2 mutations

The analysis uses data from IMPC, along with published data on other mouse mutants, in comparison to human disease reports in OMIM, Orphanet, and DECIPHER.

Phenotype comparisons summarize the similarity of mouse phenotypes with human disease phenotypes.






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Histopathology

IMPC related publications

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Ddah2tm1(KOMP)VlcgReporter-tagged deletion allele (with selection cassette)ES Cell
mouse
Ddah2tm1.1(KOMP)VlcgReporter-tagged deletion allele (post Cre, with no selection cassette)mouse
Ddah2tm1a(EUCOMM)HmguKO first allele (reporter-tagged insertion with conditional potential)targeting vector
ES Cell
Ddah2tm1e(EUCOMM)HmguTargeted, non-conditional alleleES Cell
Ddah2tm214449(L1L2_Bact_P)Reporter-tagged deletion allele (with selection cassette)targeting vector

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