Jmjd6 | jumonji domain containing 6

GeneMGI:1858910Synonyms: PSR, 5730436I23Rik, +2 more

Physiological systems

22 / 24 physiological systems tested

6 Significantly impacted by the knock-out

Immune system Vision/eye Hematopoietic system Behavior/neurological Mortality/aging Cardiovascular system

16 No significant impact

2 Not tested

Data collections

LacZ expression
Histopathology
Images
How IMPC generates data

Viability data
Body weight measurements
Embryo imaging data

Allele products available

Gene metrics:9Significant phenotypes

0Associated diseases

Expression examined in:0Adult tissues

0Embryo tissues

Phenotypes

Zygosity:

Allele:

Phy. System:



preweaning lethality, complete penetrance	1 supporting dataset	Jmjd6^{tm1a(EUCOMM)Wtsi}	homozygote	Early adult	N/A ^*
abnormal retina vasculature morphology	1 supporting dataset	Jmjd6^{tm1b(EUCOMM)Wtsi}	heterozygote	Early adult	3.91x10^-9
decreased mean platelet volume	1 supporting dataset	Jmjd6^{tm1b(EUCOMM)Wtsi}	heterozygote	Early adult	9.38x10^-7
abnormal retina morphology	1 supporting dataset	Jmjd6^{tm1b(EUCOMM)Wtsi}	heterozygote	Early adult	1.68x10^-7
abnormal lens morphology	1 supporting dataset	Jmjd6^{tm1b(EUCOMM)Wtsi}	heterozygote	Early adult	1.18x10^-5
abnormal motor coordination/balance	1 supporting dataset	Jmjd6^{tm1b(EUCOMM)Wtsi}	heterozygote	Early adult	4.91x10^-5
abnormal retina blood vessel morphology	1 supporting dataset	Jmjd6^{tm1b(EUCOMM)Wtsi}	heterozygote	Early adult	2.32x10^-8
preweaning lethality, complete penetrance	1 supporting dataset	Jmjd6^{tm1b(EUCOMM)Wtsi}	homozygote	Early adult	N/A ^*
increased NK cell number	1 supporting dataset	Jmjd6^{tm1a(EUCOMM)Wtsi}	heterozygote	Early adult	1.42x10^-6
increased startle reflex	1 supporting dataset	Jmjd6^{tm1b(EUCOMM)Wtsi}	heterozygote	Early adult	3.26x10^-5

* Does not have a P-value assigned because it was manually marked as significant.

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* This parameter was manually assessed for significance.

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lacZ Expression

No adult expression data available for Jmjd6.

Associated images

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Histopathology

There is no histopathology data found for Jmjd6.

IMPC related publications

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External links

No external links available for Jmjd6.

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*Jmjd6^{tm1a(EUCOMM)Wtsi}*	KO first allele (reporter-tagged insertion with conditional potential)	‌	targeting vector ES Cell mouse
*Jmjd6^{tm1b(EUCOMM)Wtsi}*	Reporter-tagged deletion allele (with selection cassette)	‌	mouse
*Jmjd6^{tm1e(EUCOMM)Wtsi}*	Targeted, non-conditional allele	‌	ES Cell

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