Icos | inducible T cell co-stimulator

GeneMGI:1858745

Physiological systems

9 / 24 physiological systems tested

2 Significantly impacted by the knock-out

Limbs/digits/tail Skeleton

7 No significant impact

15 Not tested

Data collections

LacZ expression
Histopathology
Images
How IMPC generates data

Viability data
Body weight measurements
Embryo imaging data

Allele products available

Gene metrics:1Significant phenotypes

2Associated diseases

Expression examined in:0Adult tissues

0Embryo tissues

Phenotypes

Phy. System:



short tibia	1 supporting dataset		Icos^{tm2b(EUCOMM)Wtsi}	homozygote	Early adult		7.02x10^-9

* Does not have a P-value assigned because it was manually marked as significant.

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* This parameter was manually assessed for significance.

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lacZ Expression

No adult expression data available for Icos.

Associated images

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Histopathology

There is no histopathology data found for Icos.

IMPC related publications

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External links

No external links available for Icos.

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*Icos^{tm1(KOMP)Vlcg}*	Reporter-tagged deletion allele (with selection cassette)	‌	es cell
*Icos^{tm1a(EUCOMM)Hmgu}*	KO first allele (reporter-tagged insertion with conditional potential)	‌	targeting vector es cell
*Icos^{tm1a(EUCOMM)Wtsi}*	KO first allele (reporter-tagged insertion with conditional potential)	‌	targeting vector es cell
*Icos^{tm1e(EUCOMM)Hmgu}*	Targeted, non-conditional allele	‌	es cell
*Icos^{tm1e(EUCOMM)Wtsi}*	Targeted, non-conditional allele	‌	es cell
*Icos^{tm2a(EUCOMM)Wtsi}*	KO first allele (reporter-tagged insertion with conditional potential)	‌	targeting vector es cell mouse
*Icos^{tm2b(EUCOMM)Wtsi}*	Reporter-tagged deletion allele (with selection cassette)	‌	mouse

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