Atp5f1e | ATP synthase F1 subunit epsilon
Physiological systems
18 / 24 physiological systems tested
2 Significantly impacted by the knock-out
Hematopoietic system Mortality/aging
16 No significant impact
6 Not tested
Data collections
Gene metrics:4Significant phenotypes
2Associated diseases
Expression examined in:45Adult tissues
0Embryo tissues
| embryonic lethality prior to organogenesis | 1 supporting dataset | Atp5f1etm1b(EUCOMM)Wtsi | homozygote | E9.5 | N/A * | ||
| preweaning lethality, complete penetrance | 1 supporting dataset | Atp5f1etm1b(EUCOMM)Wtsi | homozygote | Early adult | N/A * | ||
| increased red blood cell distribution width | 1 supporting dataset | Atp5f1etm1b(EUCOMM)Wtsi | heterozygote | Early adult | 1.71x10-6 | ||
| prenatal lethality prior to heart atrial septation | 1 supporting dataset | Atp5f1etm1b(EUCOMM)Wtsi | homozygote | E15.5 | N/A * |
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| adrenal gland | heterozygote | n/a | 100% (2/2) | 0.7% (4/570) |
| aorta | heterozygote | n/a | 0% (0/2) | 0.19% (1/533) |
| blood vessel | heterozygote | n/a | 0% (0/2) | 0% (0/173) |
| bone | heterozygote | n/a | 0% (0/2) | 0% (0/394) |
| brain | heterozygote | n/a | 100% (2/2) | 0.86% (5/579) |
| brainstem | heterozygote | n/a | 100% (2/2) | 0.41% (2/490) |
| brown adipose tissue | heterozygote | n/a | 0% (0/2) | 0% (0/588) |
| cartilage tissue | heterozygote | n/a | 100% (2/2) | 0.22% (1/454) |
| cerebellum | heterozygote | n/a | 100% (2/2) | 0.56% (3/532) |
| cerebral cortex | heterozygote | n/a | 100% (2/2) | 0.41% (2/491) |
External links
No external links available for Atp5f1e.
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| Atp5f1etm1a(EUCOMM)Wtsi | KO first allele (reporter-tagged insertion with conditional potential) | | targeting vector ES Cell mouse |
| Atp5f1etm1b(EUCOMM)Wtsi | Reporter-tagged deletion allele (with selection cassette) | | mouse |
| Atp5f1etm1e(EUCOMM)Wtsi | Targeted, non-conditional allele | | ES Cell |