Lmcd1 | LIM and cysteine-rich domains 1
Physiological systems
17 / 24 physiological systems tested
3 Significantly impacted by the knock-out
Nervous system Vision/eye Skeleton
14 No significant impact
7 Not tested
Data collections
Gene metrics:4Significant phenotypes
0Associated diseases
Expression examined in:0Adult tissues
0Embryo tissues
| decreased bone mineral content | 1 supporting dataset | Lmcd1em1(IMPC)J | homozygote | Early adult | 5.25x10-5 | ||
| decreased prepulse inhibition | 4 supporting datasets | Lmcd1em1(IMPC)J | homozygote | Early adult | 5.59x10-177 | ||
| persistence of hyaloid vascular system | 1 supporting dataset | Lmcd1em1(IMPC)J | homozygote | Early adult | 2.65x10-6 | ||
| cataract | 1 supporting dataset | Lmcd1em1(IMPC)J | homozygote | Early adult | 1.75x10-7 |
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Human diseases caused by Lmcd1 mutations
The analysis uses data from IMPC, along with published data on other mouse mutants, in comparison to human disease reports in OMIM, Orphanet, and DECIPHER.
Phenotype comparisons summarize the similarity of mouse phenotypes with human disease phenotypes.
External links
No external links available for Lmcd1.
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| Lmcd1em1(IMPC)J | Exon Deletion | | mouse |
| Lmcd1tm40401(L1L2_gt2) | KO first allele (reporter-tagged insertion with conditional potential) | | targeting vector |