Foxe3 | forkhead box E3

GeneMGI:1353569Synonyms: FREAC8, rct

Physiological systems

20 / 24 physiological systems tested

5 Significantly impacted by the knock-out

 Reproductive system Endocrine/exocrine gland Integument Vision/eye Behavior/neurological

15 No significant impact

4 Not tested

Gene metrics:9Significant phenotypes
6Associated diseases
Expression examined in:0Adult tissues
0Embryo tissues

Phenotypes

abnormal eye morphology2 supporting datasetsFoxe3em1(IMPC)MbphomozygoteEarly adultN/A * 
microphthalmia2 supporting datasetsFoxe3em1(IMPC)MbphomozygoteEarly adultN/A * 
small testis1 supporting datasetFoxe3em1(IMPC)MbphomozygoteEarly adultN/A * 
anophthalmia1 supporting datasetFoxe3em1(IMPC)MbphomozygoteEarly adultN/A * 
cornea opacity1 supporting datasetFoxe3em1(IMPC)MbphomozygoteEarly adult2.88x10-6 
abnormal testis morphology1 supporting datasetFoxe3em1(IMPC)MbphomozygoteEarly adultN/A * 
hyperactivity7 supporting datasetsFoxe3em1(IMPC)MbphomozygoteEarly adult1.22x10-7 
abnormal skin morphology1 supporting datasetFoxe3em1(IMPC)MbphomozygoteEarly adultN/A * 
increased exploration in new environment1 supporting datasetFoxe3em1(IMPC)MbphomozygoteEarly adult8.16x10-5 
* Does not have a P-value assigned because it was manually marked as significant.
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* This parameter was manually assessed for significance.
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lacZ Expression

Associated images

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Histopathology

IMPC related publications

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Foxe3em1(IMPC)MbpWhole-gene deletionmouse

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