Casr | calcium-sensing receptor
Physiological systems
21 / 24 physiological systems tested
5 Significantly impacted by the knock-out
Homeostasis/metabolism Reproductive system Endocrine/exocrine gland Nervous system Mortality/aging
16 No significant impact
3 Not tested
Data collections
Gene metrics:7Significant phenotypes
8Associated diseases
Expression examined in:0Adult tissues
0Embryo tissues
| increased circulating calcium level | 1 supporting dataset | Casrtm1b(KOMP)Mbp | heterozygote | Early adult | 4.42x10-5 | ||
| preweaning lethality, complete penetrance | 1 supporting dataset | Casrtm1b(KOMP)Mbp | homozygote | Early adult | N/A * | ||
| small superior vagus ganglion | 1 supporting dataset | Casrtm1b(KOMP)Mbp | heterozygote | Early adult | N/A * | ||
| increased circulating phosphate level | 1 supporting dataset | Casrtm1b(KOMP)Mbp | heterozygote | Early adult | 3.26x10-5 | ||
| edema | 1 supporting dataset | Casrtm1b(KOMP)Mbp | heterozygote | E15.5 | N/A * | ||
| enlarged uterus | 1 supporting dataset | Casrtm1b(KOMP)Mbp | heterozygote | Early adult | N/A * | ||
| abnormal pancreas morphology | 1 supporting dataset | Casrtm1b(KOMP)Mbp | heterozygote | Early adult | N/A * |
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External links
No external links available for Casr.
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| Casrtm1(KOMP)Vlcg | Reporter-tagged deletion allele (with selection cassette) | | es cell |
| Casrtm1a(KOMP)Mbp | KO first allele (reporter-tagged insertion with conditional potential) | | targeting vector es cell mouse |
| Casrtm1b(KOMP)Mbp | Reporter-tagged deletion allele (with selection cassette) | | mouse |