Eloa | elongin A
Physiological systems
21 / 24 physiological systems tested
6 Significantly impacted by the knock-out
Embryo Growth/size/body region Vision/eye Liver/biliary system Cardiovascular system Mortality/aging
15 No significant impact
3 Not tested
Data collections
Gene metrics:9Significant phenotypes
0Associated diseases
Expression examined in:0Adult tissues
0Embryo tissues
| small liver | 1 supporting dataset | Eloaem1(IMPC)Mbp | heterozygote | Early adult | N/A * | ||
| preweaning lethality, complete penetrance | 3 supporting datasets | Eloaem1(IMPC)Mbp | homozygote | Early adult | N/A * | ||
| abnormal heart morphology | 1 supporting dataset | Eloaem1(IMPC)Mbp | homozygote | E9.5 | N/A * | ||
| anophthalmia | 1 supporting dataset | Eloaem1(IMPC)Mbp | heterozygote | Early adult | N/A * | ||
| abnormal eye morphology | 1 supporting dataset | Eloaem1(IMPC)Mbp | heterozygote | Early adult | N/A * | ||
| abnormal liver morphology | 1 supporting dataset | Eloaem1(IMPC)Mbp | heterozygote | Early adult | N/A * | ||
| abnormal embryo turning | 1 supporting dataset | Eloaem1(IMPC)Mbp | homozygote | E9.5 | N/A * | ||
| abnormal vitreous body morphology | 1 supporting dataset | Eloaem1(IMPC)Mbp | heterozygote | Early adult | 6.46x10-5 | ||
| embryonic growth retardation | 1 supporting dataset | Eloaem1(IMPC)Mbp | homozygote | E9.5 | N/A * |
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Human diseases caused by Eloa mutations
The analysis uses data from IMPC, along with published data on other mouse mutants, in comparison to human disease reports in OMIM, Orphanet, and DECIPHER.
Phenotype comparisons summarize the similarity of mouse phenotypes with human disease phenotypes.
This gene doesn't have any significant Histopathology hits. Click here to see the raw data
External links
No external links available for Eloa.
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| Eloaem1(IMPC)Mbp | Exon Deletion | | mouse |
| Eloatm210428(L1L2_Bact_P) | KO first allele (reporter-tagged insertion with conditional potential) | | targeting vector |