Esyt1 | extended synaptotagmin-like protein 1
Physiological systems
19 / 24 physiological systems tested
5 Significantly impacted by the knock-out
Growth/size/body region Vision/eye Behavior/neurological Skeleton Craniofacial
14 No significant impact
5 Not tested
Data collections
Gene metrics:4Significant phenotypes
0Associated diseases
Expression examined in:0Adult tissues
0Embryo tissues
| abnormal tooth morphology | 2 supporting datasets | Esyt1em1(IMPC)Hmgu | homozygote | Early adult | 1.28x10-14 | ||
| abnormal gait | 1 supporting dataset | Esyt1em1(IMPC)Hmgu | homozygote | Early adult | 2x10-8 | ||
| sclerocornea | 1 supporting dataset | Esyt1em1(IMPC)Hmgu | homozygote | Early adult | 5.26x10-6 | ||
| abnormal iris transillumination | 1 supporting dataset | Esyt1em1(IMPC)Hmgu | homozygote | Early adult | 6.8x10-6 |
| | | | | | | | | | |
Human diseases caused by Esyt1 mutations
The analysis uses data from IMPC, along with published data on other mouse mutants, in comparison to human disease reports in OMIM, Orphanet, and DECIPHER.
Phenotype comparisons summarize the similarity of mouse phenotypes with human disease phenotypes.
External links
No external links available for Esyt1.
All available products are supplied via our member's centres or partnerships. When ordering a product from the IMPC you will be redirected to one of their websites or prompted to start an email.
| Esyt1em1(IMPC)Hmgu | Exon Deletion | | mouse |
| Esyt1tm1(KOMP)Vlcg | Reporter-tagged deletion allele (with selection cassette) | | ES Cell |
| Esyt1tm1a(EUCOMM)Hmgu | KO first allele (reporter-tagged insertion with conditional potential) | | targeting vector ES Cell |
| Esyt1tm1e(EUCOMM)Hmgu | Targeted, non-conditional allele | | ES Cell |