Rai2 | retinoic acid induced 2
Physiological systems
18 / 24 physiological systems tested
6 Significantly impacted by the knock-out
Limbs/digits/tail Hematopoietic system Behavior/neurological Skeleton Cardiovascular system Mortality/aging
12 No significant impact
6 Not tested
Data collections
Gene metrics:7Significant phenotypes
0Associated diseases
Expression examined in:0Adult tissues
0Embryo tissues
| short tibia | 1 supporting dataset | Rai2em1(IMPC)Bay | homozygote | Early adult | 8.24x10-5 | ||
| increased hematocrit | 1 supporting dataset | Rai2em1(IMPC)Bay | hemizygote | Early adult | 7.23x10-7 | ||
| preweaning lethality, incomplete penetrance | 1 supporting dataset | Rai2em1(IMPC)Bay | hemizygote | Early adult | N/A * | ||
| increased heart left ventricle size | 1 supporting dataset | Rai2em1(IMPC)Bay | homozygote | Early adult | 1.46x10-7 | ||
| decreased mean corpuscular hemoglobin concentration | 1 supporting dataset | Rai2em1(IMPC)Bay | hemizygote | Early adult | 3.75x10-7 | ||
| hyperactivity | 1 supporting dataset | Rai2em1(IMPC)Bay | hemizygote | Early adult | 8.92x10-5 | ||
| decreased mean corpuscular hemoglobin | 1 supporting dataset | Rai2em1(IMPC)Bay | homozygote | Early adult | 2.13x10-5 |
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Human diseases caused by Rai2 mutations
The analysis uses data from IMPC, along with published data on other mouse mutants, in comparison to human disease reports in OMIM, Orphanet, and DECIPHER.
Phenotype comparisons summarize the similarity of mouse phenotypes with human disease phenotypes.
External links
No external links available for Rai2.
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| Rai2em1(IMPC)Bay | Exon Deletion | | mouse |