Timm17b | translocase of inner mitochondrial membrane 17b
Physiological systems
16 / 24 physiological systems tested
2 Significantly impacted by the knock-out
Homeostasis/metabolism Hematopoietic system
14 No significant impact
8 Not tested
Data collections
Gene metrics:3Significant phenotypes
0Associated diseases
Expression examined in:0Adult tissues
0Embryo tissues
| decreased circulating bilirubin level | 1 supporting dataset | Timm17bem1(IMPC)J | hemizygote | Early adult | 1.31x10-5 | ||
| decreased circulating phosphate level | 1 supporting dataset | Timm17bem1(IMPC)J | hemizygote | Early adult | 9.15x10-5 | ||
| thrombocytosis | 1 supporting dataset | Timm17bem1(IMPC)J | homozygote | Early adult | 7.89x10-5 | ||
| decreased circulating bilirubin level | 1 supporting dataset | Timm17bem1(IMPC)J | homozygote | Early adult | 2.24x10-7 |
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Human diseases caused by Timm17b mutations
The analysis uses data from IMPC, along with published data on other mouse mutants, in comparison to human disease reports in OMIM, Orphanet, and DECIPHER.
Phenotype comparisons summarize the similarity of mouse phenotypes with human disease phenotypes.
External links
No external links available for Timm17b.
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| Timm17bem1(IMPC)J | Exon Deletion | | mouse |
| Timm17btm1a(KOMP)Wtsi | KO first allele (reporter-tagged insertion with conditional potential) | | targeting vector ES Cell |
| Timm17btm1e(KOMP)Wtsi | Targeted, non-conditional allele | | ES Cell |
| Timm17btm301468(L1L2_Bact_P) | KO first allele (reporter-tagged insertion with conditional potential) | | targeting vector |
| Timm17btm41082(L1L2_Bact_P) | KO first allele (reporter-tagged insertion with conditional potential) | | targeting vector |