Ube2z | ubiquitin-conjugating enzyme E2Z

GeneMGI:1343160Synonyms: C030047H17Rik

Physiological systems

17 / 24 physiological systems tested

3 Significantly impacted by the knock-out

 Immune system Hematopoietic system Cardiovascular system

14 No significant impact

7 Not tested

Data collections

LacZ expression
Histopathology
Images
How IMPC generates data
Viability data
Body weight measurements
Embryo imaging data
Gene metrics:4Significant phenotypes
0Associated diseases
Expression examined in:0Adult tissues
0Embryo tissues

Phenotypes

increased mean platelet volume1 supporting datasetUbe2zem1(IMPC)MarcheterozygoteEarly adult9.3x10-5 
decreased heart left ventricle size2 supporting datasetsUbe2zem1(IMPC)MarcheterozygoteEarly adult2.18x10-5 
increased eosinophil cell number2 supporting datasetsUbe2zem1(IMPC)MarcheterozygoteEarly adult1.14x10-16 
increased basophil cell number1 supporting datasetUbe2zem1(IMPC)MarcheterozygoteEarly adult1.35x10-6 
* Does not have a P-value assigned because it was manually marked as significant.
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* This parameter was manually assessed for significance.
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lacZ Expression

Associated images

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Histopathology

IMPC related publications

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Ube2zem1(IMPC)MarcIndelmouse
Ube2ztm366760(L1L2_Bact_P)KO first allele (reporter-tagged insertion with conditional potential)targeting vector

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