Rlim | ring finger protein, LIM domain interacting

GeneMGI:1342291Synonyms: Rlim1, Rnf12, +1 more

Physiological systems

19 / 24 physiological systems tested

6 Significantly impacted by the knock-out

 Immune system Endocrine/exocrine gland Growth/size/body region Hematopoietic system Skeleton Cardiovascular system

13 No significant impact

5 Not tested

Data collections

LacZ expression
Histopathology
Images
How IMPC generates data
Gene metrics:9Significant phenotypes
2Associated diseases
Expression examined in:0Adult tissues
0Embryo tissues

Phenotypes

abnormal thymus morphology1 supporting datasetRlimem1(IMPC)RbrcheterozygoteEarly adultN/A * 
decreased mean corpuscular hemoglobin1 supporting datasetRlimem1(IMPC)RbrchemizygoteLate adult4.67x10-5 
enlarged lymph nodes1 supporting datasetRlimem1(IMPC)RbrcheterozygoteLate adultN/A * 
enlarged heart1 supporting datasetRlimem1(IMPC)RbrcheterozygoteEarly adultN/A * 
abnormal lymph node morphology1 supporting datasetRlimem1(IMPC)RbrcheterozygoteLate adultN/A * 
fusion of vertebral arches1 supporting datasetRlimem1(IMPC)RbrchemizygoteEarly adult3.45x10-5 
abnormal heart morphology1 supporting datasetRlimem1(IMPC)RbrcheterozygoteEarly adultN/A * 
decreased mean corpuscular volume1 supporting datasetRlimem1(IMPC)RbrchemizygoteLate adult2.51x10-5 
enlarged thymus1 supporting datasetRlimem1(IMPC)RbrcheterozygoteEarly adultN/A * 
enlarged lymph nodes1 supporting datasetRlimem1(IMPC)RbrcheterozygoteEarly adultN/A * 
* Does not have a P-value assigned because it was manually marked as significant.
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* This parameter was manually assessed for significance.
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lacZ Expression

Associated images

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Histopathology

IMPC related publications

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Rlimem1(IMPC)RbrcIndelmouse
Rlimem2(IMPC)RbrcIndelmouse
Rlimtm1a(KOMP)WtsiKO first allele (reporter-tagged insertion with conditional potential)targeting vector
ES Cell
Rlimtm1e(KOMP)WtsiTargeted, non-conditional alleleES Cell
Rlimtm2a(KOMP)WtsiKO first allele (reporter-tagged insertion with conditional potential)targeting vector
ES Cell
Rlimtm2e(KOMP)WtsiTargeted, non-conditional alleleES Cell

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