Myh2 | myosin, heavy polypeptide 2, skeletal muscle, adult
Physiological systems
10 / 24 physiological systems tested
1 Significantly impacted by the knock-out
Skeleton
9 No significant impact
14 Not tested
Data collections
Gene metrics:1Significant phenotypes
3Associated diseases
Expression examined in:0Adult tissues
0Embryo tissues
| increased bone mineral content | 1 supporting dataset | Myh2em1(IMPC)Bay | homozygote | Early adult | 2.69x10-5 |
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Human diseases caused by Myh2 mutations
The analysis uses data from IMPC, along with published data on other mouse mutants, in comparison to human disease reports in OMIM, Orphanet, and DECIPHER.
Phenotype comparisons summarize the similarity of mouse phenotypes with human disease phenotypes.
External links
No external links available for Myh2.
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| Myh2em1(IMPC)Bay | Exon Deletion | | mouse |
| Myh2tm1(EGFP_CreERT2)Wtsi | Reporter-tagged deletion allele (with selection cassette) | | ES Cell |
| Myh2tm1a(KOMP)Wtsi | KO first allele (reporter-tagged insertion with conditional potential) | | targeting vector ES Cell |
| Myh2tm1e(KOMP)Wtsi | Targeted, non-conditional allele | | ES Cell |
| Myh2tm2(EGFP/cre/ERT2)Wtsi | Reporter-tagged deletion allele (with selection cassette) | | ES Cell mouse |
| Myh2tm2a(KOMP)Wtsi | KO first allele (reporter-tagged insertion with conditional potential) | | targeting vector ES Cell |
| Myh2tm2e(KOMP)Wtsi | Targeted, non-conditional allele | | ES Cell |