Spint1 | serine protease inhibitor, Kunitz type 1

GeneMGI:1338033Synonyms: HAI-1

Physiological systems

1 / 24 physiological systems tested

1 Significantly impacted by the knock-out

 Mortality/aging

23 Not tested

Data collections

LacZ expression
Histopathology
Images
How IMPC generates data
Viability data
Body weight measurements
Embryo imaging data
Gene metrics:2Significant phenotypes
0Associated diseases
Expression examined in:0Adult tissues
0Embryo tissues

Phenotypes

preweaning lethality, complete penetrance3 supporting datasetsSpint1tm1b(EUCOMM)WtsihomozygoteEarly adultN/A * 
preweaning lethality, incomplete penetrance1 supporting datasetSpint1tm1b(EUCOMM)WtsiheterozygoteEarly adultN/A * 
* Does not have a P-value assigned because it was manually marked as significant.
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* This parameter was manually assessed for significance.
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lacZ Expression

Associated images

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Histopathology

IMPC related publications

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Spint1tm1a(EUCOMM)WtsiKO first allele (reporter-tagged insertion with conditional potential)targeting vector
ES Cell
mouse
Spint1tm1b(EUCOMM)WtsiReporter-tagged deletion allele (with selection cassette)mouse
Spint1tm1e(EUCOMM)WtsiTargeted, non-conditional alleleES Cell

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