Trp73 | transformation related protein 73

GeneMGI:1336991Synonyms: deltaNp73, TAp73, +1 more

Physiological systems

17 / 24 physiological systems tested

4 Significantly impacted by the knock-out

 Homeostasis/metabolism Immune system Hematopoietic system Mortality/aging

13 No significant impact

7 Not tested

Gene metrics:4Significant phenotypes
2Associated diseases
Expression examined in:0Adult tissues
0Embryo tissues

Phenotypes

thrombocytosis1 supporting datasetTrp73em1(IMPC)HheterozygoteEarly adult7.17x10-5 
decreased spleen weight1 supporting datasetTrp73em1(IMPC)HheterozygoteEarly adult1.73x10-8 
increased blood urea nitrogen level1 supporting datasetTrp73em1(IMPC)HheterozygoteEarly adult3.69x10-5 
preweaning lethality, incomplete penetrance1 supporting datasetTrp73em1(IMPC)HhomozygoteEarly adultN/A * 
* Does not have a P-value assigned because it was manually marked as significant.
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* This parameter was manually assessed for significance.
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lacZ Expression

Associated images

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Histopathology

IMPC related publications

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Trp73em1(IMPC)HIndelmouse
Trp73em2(IMPC)HIndelmouse
Trp73tm1a(KOMP)WtsiKO first allele (reporter-tagged insertion with conditional potential)targeting vector
ES Cell

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