Mbd1 | methyl-CpG binding domain protein 1

GeneMGI:1333811Synonyms: Cxxc3, PCM1

Physiological systems

18 / 24 physiological systems tested

3 Significantly impacted by the knock-out

Reproductive system Hematopoietic system Skeleton

15 No significant impact

6 Not tested

Data collections

LacZ expression
Histopathology
Images
How IMPC generates data

Viability data
Body weight measurements
Embryo imaging data

Allele products available

Gene metrics:4Significant phenotypes

0Associated diseases

Expression examined in:0Adult tissues

0Embryo tissues

Phenotypes

Phy. System:



vertebral transformation	1 supporting dataset	Mbd1^{em1(IMPC)Wtsi}	homozygote	Early adult	3.11x10^-6
female infertility	1 supporting dataset	Mbd1^{em1(IMPC)Wtsi}	homozygote	Early adult	N/A ^*
lordosis	1 supporting dataset	Mbd1^{em1(IMPC)Wtsi}	homozygote	Early adult	1.9x10^-5
increased mean corpuscular hemoglobin	1 supporting dataset	Mbd1^{em1(IMPC)Wtsi}	homozygote	Early adult	1.79x10^-5

* Does not have a P-value assigned because it was manually marked as significant.

Download data as:

‌



‌	‌	‌	‌	‌	‌	‌	‌	‌	‌

* This parameter was manually assessed for significance.

Download data as:

lacZ Expression

No adult expression data available for Mbd1.

Associated images

Loading...

Histopathology

There is no histopathology data found for Mbd1.

IMPC related publications

Loading...

External links

No external links available for Mbd1.

Order Mouse and ES Cells

All available products are supplied via our member's centres or partnerships. When ordering a product from the IMPC you will be redirected to one of their websites or prompted to start an email.



*Mbd1^{em1(IMPC)Wtsi}*	Deletion	‌	mouse
*Mbd1^{tm1(NCOM)Mfgc}*	Reporter-tagged deletion allele (with selection cassette)	‌	targeting vector ES Cell
*Mbd1^{tm1e(EUCOMM)Hmgu}*	Targeted, non-conditional allele	‌	ES Cell
*Mbd1^{tm437424(L1L2_Bact_P)}*	KO first allele (reporter-tagged insertion with conditional potential)	‌	targeting vector

My Genes