Spa17 | sperm autoantigenic protein 17
Physiological systems
17 / 24 physiological systems tested
2 Significantly impacted by the knock-out
Reproductive system Cardiovascular system
15 No significant impact
7 Not tested
Data collections
Gene metrics:3Significant phenotypes
0Associated diseases
Expression examined in:0Adult tissues
0Embryo tissues
| male infertility | 1 supporting dataset | Spa17em1(IMPC)J | homozygote | Early adult | N/A * | ||
| decreased heart rate | 1 supporting dataset | Spa17em1(IMPC)J | homozygote | Early adult | 3.01x10-7 | ||
| prolonged RR interval | 1 supporting dataset | Spa17em1(IMPC)J | homozygote | Early adult | 2.33x10-7 |
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Human diseases caused by Spa17 mutations
The analysis uses data from IMPC, along with published data on other mouse mutants, in comparison to human disease reports in OMIM, Orphanet, and DECIPHER.
Phenotype comparisons summarize the similarity of mouse phenotypes with human disease phenotypes.
External links
No external links available for Spa17.
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| Spa17em1(IMPC)J | Exon Deletion | | mouse |
| Spa17tm87804(L1L2_Bact_P) | KO first allele (reporter-tagged insertion with conditional potential) | | targeting vector |