Cds2 | CDP-diacylglycerol synthase 2

GeneMGI:1332236Synonyms: 5730460C18Rik, 5730450N06Rik, +1 more

Physiological systems

20 / 24 physiological systems tested

2 Significantly impacted by the knock-out

Growth/size/body region Mortality/aging

18 No significant impact

4 Not tested

Data collections

LacZ expression
Histopathology
Images
How IMPC generates data

Viability data
Body weight measurements
Embryo imaging data

Allele products available

Gene metrics:2Significant phenotypes

0Associated diseases

Expression examined in:45Adult tissues

0Embryo tissues

Phenotypes

Zygosity:

Phy. System:



preweaning lethality, complete penetrance	2 supporting datasets	Cds2^{tm1a(KOMP)Wtsi}	homozygote	Early adult	N/A ^*
decreased body weight	1 supporting dataset	Cds2^{tm1a(KOMP)Wtsi}	heterozygote	Early adult	4.13x10^-5

* Does not have a P-value assigned because it was manually marked as significant.

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* This parameter was manually assessed for significance.

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lacZ Expression



adrenal gland	heterozygote	n/a	83.33% (5/6)	0.7% (4/570)
aorta	heterozygote	n/a	n/a	0.19% (1/533)
blood vessel	heterozygote	n/a	100% (5/5)	0% (0/173)
bone	heterozygote	n/a	66.67% (4/6)	0% (0/394)
brain	heterozygote	n/a	100% (6/6)	0.86% (5/579)
brainstem	heterozygote	n/a	n/a	0.41% (2/490)
brown adipose tissue	heterozygote	n/a	0% (0/6)	0% (0/588)
cartilage tissue	heterozygote	n/a	100% (5/5)	0.22% (1/454)
cerebellum	heterozygote	n/a	n/a	0.56% (3/532)
cerebral cortex	heterozygote	n/a	n/a	0.41% (2/491)

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Associated images

There are no images available for Cds2.

Histopathology

There is no histopathology data found for Cds2.

IMPC related publications

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External links

No external links available for Cds2.

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*Cds2^{tm1a(KOMP)Wtsi}*	KO first allele (reporter-tagged insertion with conditional potential)	‌	targeting vector ES Cell mouse
*Cds2^{tm1e(KOMP)Wtsi}*	Targeted, non-conditional allele	‌	ES Cell
*Cds2^{tm35224(L1L2_Bact_P)}*	KO first allele (reporter-tagged insertion with conditional potential)	‌	targeting vector
*Cds2^{tm35224(pL1L2_GT0_DelLacZ_bsd)}*	KO first allele (reporter-tagged insertion with conditional potential)	‌	targeting vector
*Cds2^{tm358049(L1L2_Bact_P)}*	KO first allele (reporter-tagged insertion with conditional potential)	‌	targeting vector

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