Lcp2 | lymphocyte cytosolic protein 2

GeneMGI:1321402Synonyms: SLP-76, SLP76, +2 more

Physiological systems

19 / 24 physiological systems tested

2 Significantly impacted by the knock-out

 Vision/eye Mortality/aging

17 No significant impact

5 Not tested

Data collections

LacZ expression
Histopathology
Images
How IMPC generates data
Gene metrics:3Significant phenotypes
1Associated diseases
Expression examined in:0Adult tissues
0Embryo tissues

Phenotypes

abnormal lens morphology1 supporting datasetLcp2tm1b(KOMP)WtsiheterozygoteEarly adult2.02x10-7 
cataract1 supporting datasetLcp2tm1b(KOMP)WtsiheterozygoteEarly adult2.02x10-7 
preweaning lethality, complete penetrance1 supporting datasetLcp2tm1b(KOMP)WtsihomozygoteEarly adultN/A * 
* Does not have a P-value assigned because it was manually marked as significant.
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* This parameter was manually assessed for significance.
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lacZ Expression

Associated images

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Histopathology

IMPC related publications

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Lcp2tm199252(L1L2_Pgk_P)KO first allele (reporter-tagged insertion with conditional potential)targeting vector
Lcp2tm1a(KOMP)WtsiKO first allele (reporter-tagged insertion with conditional potential)targeting vector
es cell
mouse
Lcp2tm1b(KOMP)WtsiReporter-tagged deletion allele (with selection cassette)mouse
Lcp2tm1e(KOMP)WtsiTargeted, non-conditional allelees cell

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