Gdf2 | growth differentiation factor 2

GeneMGI:1321394Synonyms: Bmp9

Physiological systems

21 / 24 physiological systems tested

1 Significantly impacted by the knock-out

 Hematopoietic system

20 No significant impact

3 Not tested

Gene metrics:2Significant phenotypes
3Associated diseases
Expression examined in:73Adult tissues
0Embryo tissues

Phenotypes

increased mean corpuscular volume1 supporting datasetGdf2tm1.1(KOMP)VlcghomozygoteEarly adult4.19x10-5 
* Does not have a P-value assigned because it was manually marked as significant.
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* This parameter was manually assessed for significance.
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lacZ Expression

adrenal glandheterozygoten/a0% (0/2)0.7% (4/570)
aortaheterozygoten/a0% (0/2)0.19% (1/533)
bloodheterozygoten/a0% (0/2)0% (0/17)
bone marrowheterozygoten/a0% (0/2)0% (0/22)
brainheterozygoten/a0% (0/2)0.86% (5/579)
brainstemheterozygoten/an/a0.41% (2/490)
brown adipose tissueheterozygoten/a0% (0/2)0% (0/588)
cartilage tissueheterozygoten/an/a0.22% (1/454)
cecumheterozygoten/a0% (0/2)7.75% (22/284)
cerebellumheterozygoten/a0% (0/2)0.56% (3/532)
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Histopathology

IMPC related publications

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Gdf2tm1(KOMP)VlcgReporter-tagged deletion allele (with selection cassette)ES Cell
mouse
Gdf2tm1.1(KOMP)VlcgReporter-tagged deletion allele (post Cre, with no selection cassette)mouse
Gdf2tm298094(L1L2_Bact_P)KO first allele (reporter-tagged insertion with conditional potential)targeting vector

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