Cox7a2 | cytochrome c oxidase subunit 7A2
Physiological systems
22 / 24 physiological systems tested
4 Significantly impacted by the knock-out
Homeostasis/metabolism Adipose tissue Growth/size/body region Behavior/neurological
18 No significant impact
2 Not tested
Data collections
Gene metrics:4Significant phenotypes
0Associated diseases
Expression examined in:0Adult tissues
0Embryo tissues
| decreased total body fat amount | 2 supporting datasets | Cox7a2tm1b(EUCOMM)Hmgu | heterozygote | Late adult | 8.34x10-19 | ||
| increased lean body mass | 2 supporting datasets | Cox7a2tm1b(EUCOMM)Hmgu | heterozygote | Late adult | 6.43x10-22 | ||
| increased food intake | 1 supporting dataset | Cox7a2tm1b(EUCOMM)Hmgu | heterozygote | Late adult | 3.02x10-7 | ||
| increased respiratory quotient | 1 supporting dataset | Cox7a2tm1b(EUCOMM)Hmgu | heterozygote | Late adult | 5.89x10-9 |
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Human diseases caused by Cox7a2 mutations
The analysis uses data from IMPC, along with published data on other mouse mutants, in comparison to human disease reports in OMIM, Orphanet, and DECIPHER.
Phenotype comparisons summarize the similarity of mouse phenotypes with human disease phenotypes.
External links
No external links available for Cox7a2.
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| Cox7a2tm1a(EUCOMM)Hmgu | KO first allele (reporter-tagged insertion with conditional potential) | | targeting vector ES Cell mouse |
| Cox7a2tm1b(EUCOMM)Hmgu | Reporter-tagged deletion allele (with selection cassette) | | mouse |
| Cox7a2tm1e(EUCOMM)Hmgu | Targeted, non-conditional allele | | ES Cell |