Tnfrsf1b | tumor necrosis factor receptor superfamily, member 1b

GeneMGI:1314883Synonyms: TNFalpha-R2, Tnfr2, +10 more

Physiological systems

20 / 24 physiological systems tested

5 Significantly impacted by the knock-out

Homeostasis/metabolism Immune system Nervous system Hematopoietic system Behavior/neurological

15 No significant impact

4 Not tested

Data collections

LacZ expression
Histopathology
Images
How IMPC generates data

Viability data
Body weight measurements
Embryo imaging data

Allele products available

Gene metrics:5Significant phenotypes

2Associated diseases

Expression examined in:0Adult tissues

0Embryo tissues

Phenotypes

Phy. System:



decreased prepulse inhibition	3 supporting datasets	Tnfrsf1b^{tm1a(EUCOMM)Wtsi}	homozygote	Early adult	1.44x10^-5
increased B cell number	1 supporting dataset	Tnfrsf1b^{tm1a(EUCOMM)Wtsi}	homozygote	Early adult	9.42x10^-5
increased circulating total protein level	1 supporting dataset	Tnfrsf1b^{tm1a(EUCOMM)Wtsi}	homozygote	Early adult	1.42x10^-5
decreased locomotor activity	1 supporting dataset	Tnfrsf1b^{tm1a(EUCOMM)Wtsi}	homozygote	Early adult	1.54x10^-6
decreased T cell number	1 supporting dataset	Tnfrsf1b^{tm1a(EUCOMM)Wtsi}	homozygote	Early adult	2.88x10^-5

* Does not have a P-value assigned because it was manually marked as significant.

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* This parameter was manually assessed for significance.

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lacZ Expression

No adult expression data available for Tnfrsf1b.

Associated images

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Histopathology

There is no histopathology data found for Tnfrsf1b.

IMPC related publications

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External links

No external links available for Tnfrsf1b.

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*Tnfrsf1b^{tm1a(EUCOMM)Wtsi}*	KO first allele (reporter-tagged insertion with conditional potential)	‌	targeting vector es cell mouse
*Tnfrsf1b^{tm1e(EUCOMM)Wtsi}*	Targeted, non-conditional allele	‌	es cell

My Genes