Sart1 | squamous cell carcinoma antigen recognized by T cells 1
Physiological systems
17 / 24 physiological systems tested
2 Significantly impacted by the knock-out
Behavior/neurological Mortality/aging
15 No significant impact
7 Not tested
Data collections
Gene metrics:3Significant phenotypes
0Associated diseases
Expression examined in:50Adult tissues
25Embryo tissues
| preweaning lethality, complete penetrance | 1 supporting dataset | Sart1tm1.1(KOMP)Vlcg | homozygote | Early adult | N/A * | ||
| abnormal behavior | 1 supporting dataset | Sart1tm1.1(KOMP)Vlcg | heterozygote | Early adult | 6.8x10-5 | ||
| decreased thigmotaxis | 2 supporting datasets | Sart1tm1.1(KOMP)Vlcg | heterozygote | Early adult | 6.8x10-5 |
| | | | | | | | | | |
| adrenal gland | heterozygote | Section images | 100% (2/2) | 0.7% (4/570) |
| aorta | heterozygote | Section images | 100% (2/2) | 0.19% (1/533) |
| bone | heterozygote | Section images | 100% (2/2) | 0% (0/394) |
| bone marrow | heterozygote | Section images | 100% (2/2) | 0% (0/22) |
| brain | heterozygote | Section images | 100% (2/2) | 0.86% (5/579) |
| brainstem | heterozygote | Section images | 100% (2/2) | 0.41% (2/490) |
| brown adipose tissue | heterozygote | Section images | 100% (2/2) | 0% (0/588) |
| cartilage tissue | heterozygote | Section images | 100% (2/2) | 0.22% (1/454) |
| cerebellum | heterozygote | Section images | 100% (2/2) | 0.56% (3/532) |
| cerebral cortex | heterozygote | Section images | 100% (2/2) | 0.41% (2/491) |
Human diseases caused by Sart1 mutations
The analysis uses data from IMPC, along with published data on other mouse mutants, in comparison to human disease reports in OMIM, Orphanet, and DECIPHER.
Phenotype comparisons summarize the similarity of mouse phenotypes with human disease phenotypes.
External links
No external links available for Sart1.
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