Dcx | doublecortin

GeneMGI:1277171Synonyms: lissencephaly, X-linked (doublecortin), Dbct

Physiological systems

17 / 24 physiological systems tested

1 Significantly impacted by the knock-out

Homeostasis/metabolism

16 No significant impact

7 Not tested

Data collections

LacZ expression
Histopathology
Images
How IMPC generates data

Viability data
Body weight measurements
Embryo imaging data

Allele products available

Gene metrics:3Significant phenotypes

3Associated diseases

Expression examined in:0Adult tissues

0Embryo tissues

Phenotypes



increased circulating chloride level	1 supporting dataset	Dcx^{tm1a(EUCOMM)Wtsi}	hemizygote	Early adult	6.81x10^-8
increased circulating sodium level	1 supporting dataset	Dcx^{tm1a(EUCOMM)Wtsi}	hemizygote	Early adult	9.6x10^-5
increased circulating insulin level	1 supporting dataset	Dcx^{tm1a(EUCOMM)Wtsi}	hemizygote	Early adult	3.86x10^-8

* Does not have a P-value assigned because it was manually marked as significant.

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* This parameter was manually assessed for significance.

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lacZ Expression

No adult expression data available for Dcx.

Associated images

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Histopathology

There is no histopathology data found for Dcx.

IMPC related publications

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External links

No external links available for Dcx.

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*Dcx^{tm1(KOMP)Vlcg}*	Reporter-tagged deletion allele (with selection cassette)	‌	ES Cell
*Dcx^{tm1a(EUCOMM)Wtsi}*	KO first allele (reporter-tagged insertion with conditional potential)	‌	targeting vector ES Cell mouse
*Dcx^{tm40237(L1L2_gt0)}*	KO first allele (reporter-tagged insertion with conditional potential)	‌	targeting vector

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