Parl | presenilin associated, rhomboid-like

GeneMGI:1277152Synonyms: Psarl, PRO2207, +3 more

Physiological systems

20 / 24 physiological systems tested

4 Significantly impacted by the knock-out

 Vision/eye Hematopoietic system Behavior/neurological Mortality/aging

16 No significant impact

4 Not tested

Data collections

LacZ expression
Histopathology
Images
How IMPC generates data
Viability data
Body weight measurements
Embryo imaging data
Gene metrics:4Significant phenotypes
0Associated diseases
Expression examined in:0Adult tissues
0Embryo tissues

Phenotypes

increased startle reflex1 supporting datasetParltm1a(EUCOMM)HmguheterozygoteEarly adult9.91x10-6 
increased mean corpuscular volume1 supporting datasetParltm1a(EUCOMM)HmguheterozygoteEarly adult1.88x10-5 
preweaning lethality, incomplete penetrance1 supporting datasetParltm1a(EUCOMM)HmguhomozygoteEarly adultN/A * 
cornea opacity1 supporting datasetParltm1a(EUCOMM)HmguheterozygoteEarly adult1.76x10-5 
* Does not have a P-value assigned because it was manually marked as significant.
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* This parameter was manually assessed for significance.
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lacZ Expression

Associated images

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Histopathology

IMPC related publications

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Parltm1(KOMP)VlcgReporter-tagged deletion allele (with selection cassette)ES Cell
Parltm1a(EUCOMM)HmguKO first allele (reporter-tagged insertion with conditional potential)targeting vector
ES Cell
mouse
Parltm1e(EUCOMM)HmguTargeted, non-conditional alleleES Cell
Parltm43824(L1L2_Bact_P)KO first allele (reporter-tagged insertion with conditional potential)targeting vector

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