Prep | prolyl endopeptidase
Physiological systems
19 / 24 physiological systems tested
3 Significantly impacted by the knock-out
Homeostasis/metabolism Behavior/neurological Mortality/aging
16 No significant impact
5 Not tested
Data collections
Gene metrics:6Significant phenotypes
0Associated diseases
Expression examined in:48Adult tissues
21Embryo tissues
| decreased thigmotaxis | 2 supporting datasets | Preptm1b(KOMP)Wtsi | heterozygote | Early adult | 1.86x10-5 | ||
| increased circulating sodium level | 1 supporting dataset | Preptm1b(KOMP)Wtsi | heterozygote | Early adult | 1.86x10-5 | ||
| increased circulating potassium level | 1 supporting dataset | Preptm1b(KOMP)Wtsi | heterozygote | Early adult | 2.65x10-5 | ||
| embryonic lethality prior to tooth bud stage | 1 supporting dataset | Preptm1b(KOMP)Wtsi | homozygote | E12.5 | N/A * | ||
| decreased circulating free fatty acids level | 1 supporting dataset | Preptm1b(KOMP)Wtsi | heterozygote | Early adult | 3.65x10-5 | ||
| preweaning lethality, complete penetrance | 1 supporting dataset | Preptm1b(KOMP)Wtsi | homozygote | Early adult | N/A * |
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| Preptm1a(KOMP)Wtsi | KO first allele (reporter-tagged insertion with conditional potential) | | targeting vector ES Cell mouse |
| Preptm1b(KOMP)Wtsi | Reporter-tagged deletion allele (with selection cassette) | | mouse |
| Preptm96475(L1L2_Bact_P) | KO first allele (reporter-tagged insertion with conditional potential) | | targeting vector |