Prss40 | serine protease 40

GeneMGI:1270857Synonyms: Tesp2

Physiological systems

18 / 24 physiological systems tested

18 No significant impact

6 Not tested

Gene metrics:0Significant phenotypes
0Associated diseases
Expression examined in:49Adult tissues
46Embryo tissues

Phenotypes

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* This parameter was manually assessed for significance.
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lacZ Expression

adrenal glandheterozygoten/a0% (0/2)0.7% (4/570)
aortaheterozygoten/a0% (0/2)0.19% (1/533)
bone marrowheterozygoteSection images
100% (1/1)0% (0/22)
brainheterozygoteSection images
100% (2/2)0.86% (5/579)
brainstemheterozygoteSection images
100% (2/2)0.41% (2/490)
brown adipose tissueheterozygoten/a0% (0/2)0% (0/588)
cartilage tissueheterozygoten/a0% (0/2)0.22% (1/454)
cerebellumheterozygoten/a0% (0/2)0.56% (3/532)
cerebral cortexheterozygoten/a0% (0/2)0.41% (2/491)
epididymisheterozygoten/a0% (0/1)87.5% (21/24)
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Human diseases caused by Prss40 mutations

The analysis uses data from IMPC, along with published data on other mouse mutants, in comparison to human disease reports in OMIM, Orphanet, and DECIPHER.

Phenotype comparisons summarize the similarity of mouse phenotypes with human disease phenotypes.






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Histopathology

IMPC related publications

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Order Mouse and ES Cells

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Prss40tm1a(KOMP)WtsiKO first allele (reporter-tagged insertion with conditional potential)targeting vector
ES Cell
mouse
Prss40tm1b(KOMP)WtsiReporter-tagged deletion allele (with selection cassette)mouse
Prss40tm1e(KOMP)WtsiTargeted, non-conditional alleleES Cell

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