Entpd6 | ectonucleoside triphosphate diphosphohydrolase 6

GeneMGI:1202295Synonyms: NTPDase-6, 2700026H11Rik, +1 more

Physiological systems

18 / 24 physiological systems tested

5 Significantly impacted by the knock-out

 Homeostasis/metabolism Adipose tissue Limbs/digits/tail Hematopoietic system Skeleton

13 No significant impact

6 Not tested

Data collections

LacZ expression
Histopathology
Images
How IMPC generates data
Gene metrics:5Significant phenotypes
0Associated diseases
Expression examined in:0Adult tissues
0Embryo tissues

Phenotypes

increased red blood cell distribution width1 supporting datasetEntpd6tm1a(KOMP)WtsihomozygoteEarly adult8.99x10-5 
abnormal tail morphology1 supporting datasetEntpd6tm1a(KOMP)WtsihomozygoteEarly adult6.86x10-5 
increased circulating alanine transaminase level1 supporting datasetEntpd6tm1a(KOMP)WtsihomozygoteEarly adult3.43x10-8 
decreased total body fat amount2 supporting datasetsEntpd6tm1a(KOMP)WtsihomozygoteEarly adult1.39x10-5 
decreased bone mineral content1 supporting datasetEntpd6tm1a(KOMP)WtsihomozygoteEarly adult6.53x10-5 
* Does not have a P-value assigned because it was manually marked as significant.
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* This parameter was manually assessed for significance.
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lacZ Expression

Associated images

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Histopathology

IMPC related publications

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Entpd6tm1a(KOMP)WtsiKO first allele (reporter-tagged insertion with conditional potential)targeting vector
ES Cell
mouse
Entpd6tm1e(KOMP)WtsiTargeted, non-conditional alleleES Cell
Entpd6tm2a(KOMP)WtsiKO first allele (reporter-tagged insertion with conditional potential)targeting vector
ES Cell
Entpd6tm357396(L1L2_Bact_P)KO first allele (reporter-tagged insertion with conditional potential)targeting vector

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