Slc10a2 | solute carrier family 10, member 2
Physiological systems
11 / 24 physiological systems tested
1 Significantly impacted by the knock-out
Cardiovascular system
10 No significant impact
13 Not tested
Data collections
Gene metrics:1Significant phenotypes
1Associated diseases
Expression examined in:51Adult tissues
0Embryo tissues
| increased heart left ventricle size | 1 supporting dataset | Slc10a2tm1b(KOMP)Mbp | homozygote | Early adult | 4.11x10-7 |
| | | | | | | | | | |
| adrenal gland | heterozygote | n/a | 0% (0/2) | 0.7% (4/570) |
| aorta | heterozygote | n/a | 0% (0/2) | 0.19% (1/533) |
| bone | heterozygote | n/a | 0% (0/2) | 0% (0/394) |
| brain | heterozygote | n/a | 0% (0/2) | 0.86% (5/579) |
| brainstem | heterozygote | n/a | 0% (0/2) | 0.41% (2/490) |
| brown adipose tissue | heterozygote | n/a | 0% (0/2) | 0% (0/588) |
| cartilage tissue | heterozygote | n/a | 0% (0/2) | 0.22% (1/454) |
| cecum | heterozygote | n/a | 0% (0/1) | 7.75% (22/284) |
| cerebellum | heterozygote | n/a | 0% (0/2) | 0.56% (3/532) |
| cerebral cortex | heterozygote | n/a | 0% (0/2) | 0.41% (2/491) |
Human diseases caused by Slc10a2 mutations
The analysis uses data from IMPC, along with published data on other mouse mutants, in comparison to human disease reports in OMIM, Orphanet, and DECIPHER.
Phenotype comparisons summarize the similarity of mouse phenotypes with human disease phenotypes.
External links
No external links available for Slc10a2.
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| Slc10a2tm1(EGFP_CreERT2)Wtsi | Reporter-tagged deletion allele (with selection cassette) | | ES Cell |
| Slc10a2tm1a(KOMP)Mbp | KO first allele (reporter-tagged insertion with conditional potential) | | targeting vector ES Cell mouse |
| Slc10a2tm1b(KOMP)Mbp | Reporter-tagged deletion allele (with selection cassette) | | mouse |
| Slc10a2tm1e(KOMP)Mbp | Targeted, non-conditional allele | | ES Cell |
| Slc10a2tm2a(KOMP)Mbp | KO first allele (reporter-tagged insertion with conditional potential) | | targeting vector ES Cell |
| Slc10a2tm2e(KOMP)Mbp | Targeted, non-conditional allele | | ES Cell |