Cd200 | CD200 molecule

GeneMGI:1196990Synonyms: OX2, Mox2, +1 more

Physiological systems

19 / 24 physiological systems tested

6 Significantly impacted by the knock-out

 Homeostasis/metabolism Immune system Adipose tissue Growth/size/body region Hematopoietic system Behavior/neurological

13 No significant impact

5 Not tested

Data collections

LacZ expression
Histopathology
Images
How IMPC generates data
Viability data
Body weight measurements
Embryo imaging data
Gene metrics:6Significant phenotypes
0Associated diseases
Expression examined in:0Adult tissues
0Embryo tissues

Phenotypes

decreased circulating glycerol level1 supporting datasetCd200tm1a(KOMP)WtsihomozygoteEarly adult5.52x10-6 
increased total body fat amount1 supporting datasetCd200tm1a(KOMP)WtsihomozygoteEarly adult2.35x10-11 
increased grip strength2 supporting datasetsCd200tm1a(KOMP)WtsihomozygoteEarly adult1.48x10-15 
increased lean body mass2 supporting datasetsCd200tm1a(KOMP)WtsihomozygoteEarly adult2.67x10-14 
decreased circulating calcium level1 supporting datasetCd200tm1a(KOMP)WtsihomozygoteEarly adult5.06x10-5 
decreased NK cell number1 supporting datasetCd200tm1a(KOMP)WtsihomozygoteEarly adult3.09x10-5 
* Does not have a P-value assigned because it was manually marked as significant.
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* This parameter was manually assessed for significance.
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lacZ Expression

Associated images

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Histopathology

IMPC related publications

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Cd200tm1a(KOMP)WtsiKO first allele (reporter-tagged insertion with conditional potential)targeting vector
ES Cell
mouse
Cd200tm1e(KOMP)WtsiTargeted, non-conditional alleleES Cell

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