Cd200 | CD200 molecule
Physiological systems
19 / 24 physiological systems tested
6 Significantly impacted by the knock-out
Homeostasis/metabolism Immune system Adipose tissue Growth/size/body region Hematopoietic system Behavior/neurological
13 No significant impact
5 Not tested
Data collections
Viability data
Body weight measurements
Embryo imaging data
Body weight measurements
Embryo imaging data
Gene metrics:6Significant phenotypes
0Associated diseases
Expression examined in:0Adult tissues
0Embryo tissues
| decreased circulating glycerol level | 1 supporting dataset | Cd200tm1a(KOMP)Wtsi | homozygote | Early adult | 5.52x10-6 | ||
| increased total body fat amount | 1 supporting dataset | Cd200tm1a(KOMP)Wtsi | homozygote | Early adult | 2.35x10-11 | ||
| increased grip strength | 2 supporting datasets | Cd200tm1a(KOMP)Wtsi | homozygote | Early adult | 1.48x10-15 | ||
| increased lean body mass | 2 supporting datasets | Cd200tm1a(KOMP)Wtsi | homozygote | Early adult | 2.67x10-14 | ||
| decreased circulating calcium level | 1 supporting dataset | Cd200tm1a(KOMP)Wtsi | homozygote | Early adult | 5.06x10-5 | ||
| decreased NK cell number | 1 supporting dataset | Cd200tm1a(KOMP)Wtsi | homozygote | Early adult | 3.09x10-5 |
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Human diseases caused by Cd200 mutations
The analysis uses data from IMPC, along with published data on other mouse mutants, in comparison to human disease reports in OMIM, Orphanet, and DECIPHER.
Phenotype comparisons summarize the similarity of mouse phenotypes with human disease phenotypes.
External links
No external links available for Cd200.
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| Cd200tm1a(KOMP)Wtsi | KO first allele (reporter-tagged insertion with conditional potential) | | targeting vector ES Cell mouse |
| Cd200tm1e(KOMP)Wtsi | Targeted, non-conditional allele | | ES Cell |