Rbpjl | recombination signal binding protein for immunoglobulin kappa J region-like

GeneMGI:1196616Synonyms: RBP-L, Rbpsuhl, +1 more

Physiological systems

17 / 24 physiological systems tested

2 Significantly impacted by the knock-out

Homeostasis/metabolism Behavior/neurological

15 No significant impact

7 Not tested

Data collections

LacZ expression
Histopathology
Images
How IMPC generates data

Viability data
Body weight measurements
Embryo imaging data

Allele products available

Gene metrics:3Significant phenotypes

0Associated diseases

Expression examined in:46Adult tissues

42Embryo tissues

Phenotypes

Phy. System:



decreased locomotor activity	4 supporting datasets	Rbpjl^{tm1b(KOMP)Wtsi}	homozygote	Early adult	1.05x10^-5
increased circulating amylase level	1 supporting dataset	Rbpjl^{tm1b(KOMP)Wtsi}	homozygote	Early adult	2.19x10^-5
head bobbing	1 supporting dataset	Rbpjl^{tm1b(KOMP)Wtsi}	homozygote	Early adult	7.19x10^-5

* Does not have a P-value assigned because it was manually marked as significant.

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* This parameter was manually assessed for significance.

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lacZ Expression



adrenal gland	heterozygote	n/a	0% (0/2)	0.7% (4/570)
aorta	heterozygote	n/a	0% (0/2)	0.19% (1/533)
bone	heterozygote	n/a	0% (0/2)	0% (0/394)
brain	heterozygote	n/a	0% (0/2)	0.86% (5/579)
brainstem	heterozygote	n/a	0% (0/2)	0.41% (2/490)
brown adipose tissue	heterozygote	n/a	0% (0/2)	0% (0/588)
cartilage tissue	heterozygote	n/a	0% (0/2)	0.22% (1/454)
cerebellum	heterozygote	n/a	0% (0/2)	0.56% (3/532)
cerebral cortex	heterozygote	n/a	0% (0/2)	0.41% (2/491)
esophagus	heterozygote	n/a	0% (0/2)	1.67% (7/419)

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Associated images

4 images

Adult LacZ

LacZ Images Wholemount

Download files

Auditory Brain Stem Response

Click-evoked + 6 to 30kHz tone waveforms (pdf format)

8 images

Embryo LacZ

LacZ images wholemount

10 images

X-ray

XRay Images Skull Dorso Ventral Orientation

10 images

X-ray

XRay Images Whole Body Dorso Ventral

10 images

X-ray

XRay Images Whole Body Lateral Orientation

Histopathology

There is no histopathology data found for Rbpjl.

IMPC related publications

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External links

No external links available for Rbpjl.

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*Rbpjl^{tm1(EGFP_CreERT2)Wtsi}*	Reporter-tagged deletion allele (with selection cassette)	‌	ES Cell mouse
*Rbpjl^{tm1a(KOMP)Wtsi}*	KO first allele (reporter-tagged insertion with conditional potential)	‌	targeting vector ES Cell mouse
*Rbpjl^{tm1b(KOMP)Wtsi}*	Reporter-tagged deletion allele (with selection cassette)	‌	mouse
*Rbpjl^{tm1e(KOMP)Wtsi}*	Targeted, non-conditional allele	‌	ES Cell

My Genes

Rbpjl | recombination signal binding protein for immunoglobulin kappa J region-like

Physiological systems

2 Significantly impacted by the knock-out

15 No significant impact

7 Not tested

Data collections

Phenotypes

lacZ Expression

Associated images

Adult LacZ

Auditory Brain Stem Response

Embryo LacZ

X-ray

X-ray

X-ray

Histopathology

IMPC related publications

External links

Order Mouse and ES Cells

The IMPC Newsletter

Access Data Release 22.1 Data