Prag1 | PEAK1 related kinase activating pseudokinase 1

GeneMGI:1196223Synonyms: NACK, D8Ertd82e

Physiological systems

17 / 24 physiological systems tested

2 Significantly impacted by the knock-out

 Homeostasis/metabolism Nervous system

15 No significant impact

7 Not tested

Gene metrics:2Significant phenotypes
0Associated diseases
Expression examined in:0Adult tissues
0Embryo tissues

Phenotypes

decreased fasting circulating glucose level1 supporting datasetPrag1em2(IMPC)TcphomozygoteEarly adult1.04x10-5 
decreased prepulse inhibition1 supporting datasetPrag1em2(IMPC)TcphomozygoteEarly adult6.13x10-5 
* Does not have a P-value assigned because it was manually marked as significant.
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* This parameter was manually assessed for significance.
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lacZ Expression

Associated images

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Histopathology

IMPC related publications

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Prag1em2(IMPC)TcpIntra-exon deletionmouse
Prag1tm1a(KOMP)MbpKO first allele (reporter-tagged insertion with conditional potential)targeting vector
ES Cell
Prag1tm1e(KOMP)MbpTargeted, non-conditional alleleES Cell
Prag1tm1e(KOMP)WtsiTargeted, non-conditional alleleES Cell
Prag1tm41666(L1L2_gt0)KO first allele (reporter-tagged insertion with conditional potential)targeting vector

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