Abce1 | ATP-binding cassette, sub-family E member 1

GeneMGI:1195458Synonyms: Rnaseli, RNS4l (Eye), +1 more

Physiological systems

18 / 24 physiological systems tested

8 Significantly impacted by the knock-out

Homeostasis/metabolism Reproductive system Immune system Endocrine/exocrine gland Nervous system Vision/eye Hematopoietic system Mortality/aging

10 No significant impact

6 Not tested

Data collections

LacZ expression
Histopathology
Images
How IMPC generates data

Viability data
Body weight measurements
Embryo imaging data

Allele products available

Gene metrics:13Significant phenotypes

0Associated diseases

Expression examined in:0Adult tissues

0Embryo tissues

Phenotypes

Zygosity:

Allele:

Phy. System:

Life Stage:



decreased prepulse inhibition	4 supporting datasets	Abce1^{tm1.1(KOMP)Vlcg}	heterozygote	Early adult	3.18x10^-7
preweaning lethality, complete penetrance	3 supporting datasets	Abce1^{tm1.1(KOMP)Vlcg}	homozygote	Early adult	N/A ^*
increased neutrophil cell number	1 supporting dataset	Abce1^{tm1.1(KOMP)Vlcg}	heterozygote	Early adult	4.54x10^-7
increased large unstained cell number	1 supporting dataset	Abce1^{tm1b(EUCOMM)Hmgu}	heterozygote	Early adult	1.57x10^-9
anophthalmia	1 supporting dataset	Abce1^{tm1b(EUCOMM)Hmgu}	heterozygote	Early adult	4.38x10^-5
enlarged lymph nodes	1 supporting dataset	Abce1^{tm1.1(KOMP)Vlcg}	heterozygote	Early adult	N/A ^*
abnormal seminal vesicle morphology	1 supporting dataset	Abce1^{tm1.1(KOMP)Vlcg}	heterozygote	Early adult	N/A ^*
decreased circulating creatinine level	1 supporting dataset	Abce1^{tm1b(EUCOMM)Hmgu}	heterozygote	Early adult	2.36x10^-5
preweaning lethality, complete penetrance	1 supporting dataset	Abce1^{tm1b(EUCOMM)Hmgu}	homozygote	Early adult	N/A ^*
embryonic lethality prior to organogenesis	1 supporting dataset	Abce1^{tm1b(EUCOMM)Hmgu}	homozygote	E9.5	N/A ^*

* Does not have a P-value assigned because it was manually marked as significant.

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* This parameter was manually assessed for significance.

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lacZ Expression

No adult expression data available for Abce1.

Associated images

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Histopathology

There is no histopathology data found for Abce1.

IMPC related publications

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External links

No external links available for Abce1.

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*Abce1^{tm1(KOMP)Vlcg}*	Reporter-tagged deletion allele (with selection cassette)	‌	es cell mouse
*Abce1^{tm1.1(KOMP)Vlcg}*	Reporter-tagged deletion allele (post Cre, with no selection cassette)	‌	mouse
*Abce1^{tm1a(EUCOMM)Hmgu}*	KO first allele (reporter-tagged insertion with conditional potential)	‌	targeting vector es cell mouse
*Abce1^{tm1b(EUCOMM)Hmgu}*	Reporter-tagged deletion allele (with selection cassette)	‌	mouse
*Abce1^{tm1e(EUCOMM)Hmgu}*	Targeted, non-conditional allele	‌	es cell

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