Fpr3 | formyl peptide receptor 3
Physiological systems
20 / 24 physiological systems tested
5 Significantly impacted by the knock-out
Homeostasis/metabolism Digestive/alimentary Vision/eye Hematopoietic system Behavior/neurological
15 No significant impact
4 Not tested
Data collections
Gene metrics:8Significant phenotypes
0Associated diseases
Expression examined in:0Adult tissues
0Embryo tissues
| decreased exploration in new environment | 1 supporting dataset | Fpr3tm1b(EUCOMM)Hmgu | homozygote | Early adult | 1.72x10-5 | ||
| persistence of hyaloid vascular system | 1 supporting dataset | Fpr3tm1b(EUCOMM)Hmgu | homozygote | Early adult | 4.11x10-6 | ||
| abnormal vitreous body morphology | 1 supporting dataset | Fpr3tm1b(EUCOMM)Hmgu | homozygote | Early adult | 7.01x10-5 | ||
| increased hemoglobin content | 1 supporting dataset | Fpr3tm1b(EUCOMM)Hmgu | homozygote | Early adult | 6.84x10-6 | ||
| increased circulating cholesterol level | 1 supporting dataset | Fpr3tm1b(EUCOMM)Hmgu | homozygote | Early adult | 7.37x10-5 | ||
| increased hematocrit | 1 supporting dataset | Fpr3tm1b(EUCOMM)Hmgu | homozygote | Early adult | 9.95x10-7 | ||
| abnormal ileum morphology | 1 supporting dataset | Fpr3tm1b(EUCOMM)Hmgu | homozygote | Early adult | N/A * | ||
| abnormal colon morphology | 1 supporting dataset | Fpr3tm1b(EUCOMM)Hmgu | homozygote | Early adult | N/A * |
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Human diseases caused by Fpr3 mutations
The analysis uses data from IMPC, along with published data on other mouse mutants, in comparison to human disease reports in OMIM, Orphanet, and DECIPHER.
Phenotype comparisons summarize the similarity of mouse phenotypes with human disease phenotypes.
External links
No external links available for Fpr3.
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| Fpr3tm1a(EUCOMM)Hmgu | KO first allele (reporter-tagged insertion with conditional potential) | | targeting vector ES Cell mouse |
| Fpr3tm1b(EUCOMM)Hmgu | Reporter-tagged deletion allele (with selection cassette) | | mouse |
| Fpr3tm1e(EUCOMM)Hmgu | Targeted, non-conditional allele | | ES Cell |