Fpr3 | formyl peptide receptor 3

GeneMGI:1194495Synonyms: Fprl1, Fpr-rs1, +2 more

Physiological systems

20 / 24 physiological systems tested

5 Significantly impacted by the knock-out

 Homeostasis/metabolism Digestive/alimentary Vision/eye Hematopoietic system Behavior/neurological

15 No significant impact

4 Not tested

Data collections

LacZ expression
Histopathology
Images
How IMPC generates data
Gene metrics:8Significant phenotypes
0Associated diseases
Expression examined in:0Adult tissues
0Embryo tissues

Phenotypes

decreased exploration in new environment1 supporting datasetFpr3tm1b(EUCOMM)HmguhomozygoteEarly adult1.72x10-5 
persistence of hyaloid vascular system1 supporting datasetFpr3tm1b(EUCOMM)HmguhomozygoteEarly adult4.11x10-6 
abnormal vitreous body morphology1 supporting datasetFpr3tm1b(EUCOMM)HmguhomozygoteEarly adult7.01x10-5 
increased hemoglobin content1 supporting datasetFpr3tm1b(EUCOMM)HmguhomozygoteEarly adult6.84x10-6 
increased circulating cholesterol level1 supporting datasetFpr3tm1b(EUCOMM)HmguhomozygoteEarly adult7.37x10-5 
increased hematocrit1 supporting datasetFpr3tm1b(EUCOMM)HmguhomozygoteEarly adult9.95x10-7 
abnormal ileum morphology1 supporting datasetFpr3tm1b(EUCOMM)HmguhomozygoteEarly adultN/A * 
abnormal colon morphology1 supporting datasetFpr3tm1b(EUCOMM)HmguhomozygoteEarly adultN/A * 
* Does not have a P-value assigned because it was manually marked as significant.
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* This parameter was manually assessed for significance.
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lacZ Expression

Associated images

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Histopathology

IMPC related publications

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Fpr3tm1a(EUCOMM)HmguKO first allele (reporter-tagged insertion with conditional potential)targeting vector
es cell
mouse
Fpr3tm1b(EUCOMM)HmguReporter-tagged deletion allele (with selection cassette)mouse
Fpr3tm1e(EUCOMM)HmguTargeted, non-conditional allelees cell

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