Capn5 | calpain 5

Physiological systems

20 / 24 physiological systems tested

2 Significantly impacted by the knock-out

 Homeostasis/metabolism Behavior/neurological

18 No significant impact

4 Not tested

Data collections

LacZ expression
Histopathology
Images
How IMPC generates data
Viability data
Body weight measurements
Embryo imaging data
Gene metrics:2Significant phenotypes
2Associated diseases
Expression examined in:0Adult tissues
0Embryo tissues

Phenotypes

increased startle reflex2 supporting datasetsCapn5tm1a(EUCOMM)HmguhomozygoteEarly adult4.24x10-7 
decreased circulating serum albumin level1 supporting datasetCapn5tm1a(EUCOMM)HmguhomozygoteEarly adult6.75x10-5 
* Does not have a P-value assigned because it was manually marked as significant.
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* This parameter was manually assessed for significance.
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lacZ Expression

Associated images

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Histopathology

IMPC related publications

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Capn5tm1a(EUCOMM)HmguKO first allele (reporter-tagged insertion with conditional potential)targeting vector
es cell
mouse
Capn5tm1e(EUCOMM)HmguTargeted, non-conditional allelees cell

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