Pitx3 | paired-like homeodomain transcription factor 3
Physiological systems
21 / 24 physiological systems tested
5 Significantly impacted by the knock-out
Homeostasis/metabolism Growth/size/body region Vision/eye Behavior/neurological Cardiovascular system
16 No significant impact
3 Not tested
Data collections
Gene metrics:17Significant phenotypes
4Associated diseases
Expression examined in:48Adult tissues
53Embryo tissues
| decreased vertical activity | 1 supporting dataset | Pitx3tm1.1(KOMP)Vlcg | homozygote | Early adult | 5.87x10-7 | ||
| increased coping response | 1 supporting dataset | Pitx3tm1.1(KOMP)Vlcg | homozygote | Early adult | 7.94x10-9 | ||
| abnormal sleep behavior | 7 supporting datasets | Pitx3tm1.1(KOMP)Vlcg | homozygote | Early adult | 2.06x10-32 | ||
| decreased locomotor activity | 1 supporting dataset | Pitx3eyl | homozygote | Early adult | 5.09x10-5 | ||
| hyperactivity | 7 supporting datasets | Pitx3tm1.1(KOMP)Vlcg | homozygote | Early adult | 1.35x10-28 | ||
| decreased circulating free fatty acids level | 1 supporting dataset | Pitx3tm1.1(KOMP)Vlcg | homozygote | Early adult | 3.97x10-5 | ||
| increased grip strength | 1 supporting dataset | Pitx3tm1.1(KOMP)Vlcg | homozygote | Early adult | 4.16x10-5 | ||
| abnormal motor coordination/balance | 1 supporting dataset | Pitx3tm1.1(KOMP)Vlcg | homozygote | Early adult | 6.97x10-5 | ||
| decreased body weight | 4 supporting datasets | Pitx3eyl | homozygote | Early adult | 2.12x10-6 | ||
| decreased vertical activity | 1 supporting dataset | Pitx3eyl | homozygote | Early adult | 4.05x10-8 |
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External links
No external links available for Pitx3.
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