Kif5c | kinesin family member 5C
Physiological systems
16 / 24 physiological systems tested
3 Significantly impacted by the knock-out
Homeostasis/metabolism Immune system Hematopoietic system
13 No significant impact
8 Not tested
Data collections
Gene metrics:3Significant phenotypes
1Associated diseases
Expression examined in:0Adult tissues
0Embryo tissues
| increased circulating total protein level | 1 supporting dataset | Kif5ctm1dIcs | heterozygote | Early adult | 8.91x10-5 | ||
| increased eosinophil cell number | 1 supporting dataset | Kif5ctm1dIcs | heterozygote | Early adult | 4.92x10-7 | ||
| decreased lymphocyte cell number | 1 supporting dataset | Kif5ctm1dIcs | heterozygote | Early adult | 1.43x10-5 |
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Human diseases caused by Kif5c mutations
The analysis uses data from IMPC, along with published data on other mouse mutants, in comparison to human disease reports in OMIM, Orphanet, and DECIPHER.
Phenotype comparisons summarize the similarity of mouse phenotypes with human disease phenotypes.
External links
No external links available for Kif5c.
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| Kif5ctm1aIcs | KO first allele (reporter-tagged insertion with conditional potential) | | ES Cell mouse |
| Kif5ctm1dIcs | Deletion allele (post-Flp and Cre with no reporter) | | mouse |
| Kif5ctm1e(KOMP)Wtsi | Targeted, non-conditional allele | | ES Cell |
| Kif5ctm87138(L1L2_Bact_P) | KO first allele (reporter-tagged insertion with conditional potential) | | targeting vector |