Bhlhe40 | basic helix-loop-helix family, member e40
Physiological systems
19 / 24 physiological systems tested
4 Significantly impacted by the knock-out
Homeostasis/metabolism Growth/size/body region Hematopoietic system Cardiovascular system
15 No significant impact
5 Not tested
Data collections
Gene metrics:11Significant phenotypes
0Associated diseases
Expression examined in:49Adult tissues
50Embryo tissues
| increased blood urea nitrogen level | 1 supporting dataset | Bhlhe40tm1b(KOMP)Wtsi | homozygote | Early adult | 6.31x10-6 | ||
| decreased circulating glycerol level | 1 supporting dataset | Bhlhe40tm1b(KOMP)Wtsi | homozygote | Early adult | 1.01x10-5 | ||
| increased circulating chloride level | 1 supporting dataset | Bhlhe40tm1b(KOMP)Wtsi | homozygote | Early adult | 7x10-5 | ||
| decreased circulating HDL cholesterol level | 1 supporting dataset | Bhlhe40tm1b(KOMP)Wtsi | homozygote | Early adult | 2.81x10-7 | ||
| decreased fasting circulating glucose level | 1 supporting dataset | Bhlhe40tm1b(KOMP)Wtsi | homozygote | Early adult | 3.51x10-6 | ||
| decreased circulating cholesterol level | 1 supporting dataset | Bhlhe40tm1b(KOMP)Wtsi | homozygote | Early adult | 2.89x10-5 | ||
| increased mean corpuscular hemoglobin | 1 supporting dataset | Bhlhe40tm1b(KOMP)Wtsi | homozygote | Early adult | 9.18x10-7 | ||
| increased heart weight | 1 supporting dataset | Bhlhe40tm1b(KOMP)Wtsi | homozygote | Early adult | 6.16x10-6 | ||
| increased circulating fructosamine level | 1 supporting dataset | Bhlhe40tm1b(KOMP)Wtsi | homozygote | Early adult | 2.23x10-10 | ||
| decreased circulating calcium level | 1 supporting dataset | Bhlhe40tm1b(KOMP)Wtsi | homozygote | Early adult | 9.41x10-5 |
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| adrenal gland | heterozygote | Section images | 100% (2/2) | 0.7% (4/570) |
| aorta | heterozygote | Section images | 100% (2/2) | 0.19% (1/533) |
| bone marrow | heterozygote | Section images | 100% (2/2) | 0% (0/22) |
| brain | heterozygote | Section images | 100% (2/2) | 0.86% (5/579) |
| brainstem | heterozygote | Section images | 100% (2/2) | 0.41% (2/490) |
| brown adipose tissue | heterozygote | Section images | 100% (2/2) | 0% (0/588) |
| cartilage tissue | heterozygote | Section images | 100% (2/2) | 0.22% (1/454) |
| cerebellum | heterozygote | Section images | 100% (2/2) | 0.56% (3/532) |
| cerebral cortex | heterozygote | Section images | 100% (2/2) | 0.41% (2/491) |
| epididymis | heterozygote | Section images | 100% (1/1) | 87.5% (21/24) |
External links
No external links available for Bhlhe40.
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| Bhlhe40tm1a(KOMP)Wtsi | KO first allele (reporter-tagged insertion with conditional potential) | | targeting vector ES Cell mouse |
| Bhlhe40tm1b(KOMP)Wtsi | Reporter-tagged deletion allele (with selection cassette) | | mouse |