Tex261 | testis expressed gene 261

GeneMGI:1096575Synonyms: TEG-261, 3110001O07Rik

Physiological systems

15 / 24 physiological systems tested

6 Significantly impacted by the knock-out

Homeostasis/metabolism Immune system Adipose tissue Growth/size/body region Hematopoietic system Skeleton

9 No significant impact

9 Not tested

Data collections

LacZ expression
Histopathology
Images
How IMPC generates data

Viability data
Body weight measurements
Embryo imaging data

Allele products available

Gene metrics:17Significant phenotypes

0Associated diseases

Expression examined in:0Adult tissues

0Embryo tissues

Phenotypes

Phy. System:



increased bone mineral content	2 supporting datasets	Tex261^{tm1b(EUCOMM)Wtsi}	homozygote	Early adult	5.72x10^-8
increased red blood cell distribution width	1 supporting dataset	Tex261^{tm1b(EUCOMM)Wtsi}	homozygote	Early adult	8.6x10^-8
decreased circulating calcium level	1 supporting dataset	Tex261^{tm1b(EUCOMM)Wtsi}	homozygote	Early adult	6.37x10^-7
decreased circulating total protein level	1 supporting dataset	Tex261^{tm1b(EUCOMM)Wtsi}	homozygote	Early adult	2.38x10^-5
increased bone mineral density	1 supporting dataset	Tex261^{tm1b(EUCOMM)Wtsi}	homozygote	Early adult	1.25x10^-6
decreased hemoglobin content	1 supporting dataset	Tex261^{tm1b(EUCOMM)Wtsi}	homozygote	Early adult	5.27x10^-6
decreased circulating serum albumin level	1 supporting dataset	Tex261^{tm1b(EUCOMM)Wtsi}	homozygote	Early adult	1.93x10^-5
decreased circulating LDL cholesterol level	1 supporting dataset	Tex261^{tm1b(EUCOMM)Wtsi}	homozygote	Early adult	5.33x10^-6
decreased circulating HDL cholesterol level	1 supporting dataset	Tex261^{tm1b(EUCOMM)Wtsi}	homozygote	Early adult	5.04x10^-13
decreased circulating cholesterol level	1 supporting dataset	Tex261^{tm1b(EUCOMM)Wtsi}	homozygote	Early adult	5.45x10^-11

* Does not have a P-value assigned because it was manually marked as significant.

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* This parameter was manually assessed for significance.

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lacZ Expression

No adult expression data available for Tex261.

Associated images

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Histopathology

There is no histopathology data found for Tex261.

IMPC related publications

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External links

No external links available for Tex261.

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*Tex261^{tm1a(EUCOMM)Hmgu}*	KO first allele (reporter-tagged insertion with conditional potential)	‌	targeting vector ES Cell
*Tex261^{tm1a(EUCOMM)Wtsi}*	KO first allele (reporter-tagged insertion with conditional potential)	‌	targeting vector ES Cell mouse
*Tex261^{tm1b(EUCOMM)Wtsi}*	Reporter-tagged deletion allele (with selection cassette)	‌	mouse
*Tex261^{tm1e(EUCOMM)Hmgu}*	Targeted, non-conditional allele	‌	ES Cell
*Tex261^{tm1e(EUCOMM)Wtsi}*	Targeted, non-conditional allele	‌	ES Cell

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