Ackr3 | atypical chemokine receptor 3
Physiological systems
19 / 24 physiological systems tested
4 Significantly impacted by the knock-out
Vision/eye Hematopoietic system Behavior/neurological Mortality/aging
15 No significant impact
5 Not tested
Data collections
Gene metrics:5Significant phenotypes
1Associated diseases
Expression examined in:0Adult tissues
0Embryo tissues
| decreased total retina thickness | 2 supporting datasets | Ackr3tm2b(EUCOMM)Wtsi | heterozygote | Early adult | 2.16x10-5 | ||
| decreased grip strength | 2 supporting datasets | Ackr3tm2b(EUCOMM)Wtsi | heterozygote | Early adult | 2.09x10-6 | ||
| preweaning lethality, complete penetrance | 1 supporting dataset | Ackr3tm2b(EUCOMM)Wtsi | homozygote | Early adult | N/A * | ||
| increased mean corpuscular hemoglobin concentration | 1 supporting dataset | Ackr3tm2b(EUCOMM)Wtsi | heterozygote | Early adult | 1.6x10-5 | ||
| tremors | 1 supporting dataset | Ackr3tm2b(EUCOMM)Wtsi | heterozygote | Early adult | 7.93x10-5 |
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External links
No external links available for Ackr3.
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| Ackr3tm1(KOMP)Vlcg | Reporter-tagged deletion allele (with selection cassette) | | es cell |
| Ackr3tm2a(EUCOMM)Wtsi | KO first allele (reporter-tagged insertion with conditional potential) | | targeting vector es cell mouse |
| Ackr3tm2b(EUCOMM)Wtsi | Reporter-tagged deletion allele (with selection cassette) | | mouse |
| Ackr3tm2e(EUCOMM)Wtsi | Targeted, non-conditional allele | | es cell |