Ackr3 | atypical chemokine receptor 3

GeneMGI:109562Synonyms: Rdc1, Cxcr7, +1 more

Physiological systems

19 / 24 physiological systems tested

4 Significantly impacted by the knock-out

Vision/eye Hematopoietic system Behavior/neurological Mortality/aging

15 No significant impact

5 Not tested

Data collections

LacZ expression
Histopathology
Images
How IMPC generates data

Viability data
Body weight measurements
Embryo imaging data

Allele products available

Gene metrics:5Significant phenotypes

1Associated diseases

Expression examined in:0Adult tissues

0Embryo tissues

Phenotypes

Zygosity:

Phy. System:



decreased total retina thickness	2 supporting datasets	Ackr3^{tm2b(EUCOMM)Wtsi}	heterozygote	Early adult	2.16x10^-5
decreased grip strength	2 supporting datasets	Ackr3^{tm2b(EUCOMM)Wtsi}	heterozygote	Early adult	2.09x10^-6
preweaning lethality, complete penetrance	1 supporting dataset	Ackr3^{tm2b(EUCOMM)Wtsi}	homozygote	Early adult	N/A ^*
increased mean corpuscular hemoglobin concentration	1 supporting dataset	Ackr3^{tm2b(EUCOMM)Wtsi}	heterozygote	Early adult	1.6x10^-5
tremors	1 supporting dataset	Ackr3^{tm2b(EUCOMM)Wtsi}	heterozygote	Early adult	7.93x10^-5

* Does not have a P-value assigned because it was manually marked as significant.

Download data as:

‌



‌	‌	‌	‌	‌	‌	‌	‌	‌	‌

* This parameter was manually assessed for significance.

Download data as:

lacZ Expression

No adult expression data available for Ackr3.

Associated images

Loading...

Histopathology

There is no histopathology data found for Ackr3.

IMPC related publications

Loading...

External links

No external links available for Ackr3.

Order Mouse and ES Cells

All available products are supplied via our member's centres or partnerships. When ordering a product from the IMPC you will be redirected to one of their websites or prompted to start an email.



*Ackr3^{tm1(KOMP)Vlcg}*	Reporter-tagged deletion allele (with selection cassette)	‌	ES Cell
*Ackr3^{tm2a(EUCOMM)Wtsi}*	KO first allele (reporter-tagged insertion with conditional potential)	‌	targeting vector ES Cell mouse
*Ackr3^{tm2b(EUCOMM)Wtsi}*	Reporter-tagged deletion allele (with selection cassette)	‌	mouse
*Ackr3^{tm2e(EUCOMM)Wtsi}*	Targeted, non-conditional allele	‌	ES Cell

My Genes