Msh3 | mutS homolog 3
Physiological systems
20 / 24 physiological systems tested
4 Significantly impacted by the knock-out
Integument Growth/size/body region Vision/eye Renal/urinary system
16 No significant impact
4 Not tested
Data collections
Gene metrics:5Significant phenotypes
3Associated diseases
Expression examined in:0Adult tissues
0Embryo tissues
| cataract | 1 supporting dataset | Msh3em1(IMPC)Mbp | homozygote | Early adult | 6.35x10-5 | ||
| abnormal skin morphology | 1 supporting dataset | Msh3em1(IMPC)Mbp | homozygote | Early adult | N/A * | ||
| abnormal vitreous body morphology | 1 supporting dataset | Msh3em1(IMPC)Mbp | homozygote | Early adult | 5.99x10-5 | ||
| enlarged kidney | 1 supporting dataset | Msh3em1(IMPC)Mbp | homozygote | Early adult | N/A * | ||
| abnormal kidney morphology | 1 supporting dataset | Msh3em1(IMPC)Mbp | homozygote | Early adult | N/A * |
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Human diseases caused by Msh3 mutations
The analysis uses data from IMPC, along with published data on other mouse mutants, in comparison to human disease reports in OMIM, Orphanet, and DECIPHER.
Phenotype comparisons summarize the similarity of mouse phenotypes with human disease phenotypes.
This gene doesn't have any significant Histopathology hits. Click here to see the raw data
External links
No external links available for Msh3.
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| Msh3em1(IMPC)Mbp | Exon Deletion | | mouse |