Cbx5 | chromobox 5

GeneMGI:109372Synonyms: heterochromatin protein 1 alpha, 2610029O15Rik, +4 more

Physiological systems

17 / 24 physiological systems tested

3 Significantly impacted by the knock-out

Homeostasis/metabolism Behavior/neurological Skeleton

14 No significant impact

7 Not tested

Data collections

LacZ expression
Histopathology
Images
How IMPC generates data

Viability data
Body weight measurements
Embryo imaging data

Allele products available

Gene metrics:5Significant phenotypes

0Associated diseases

Expression examined in:0Adult tissues

0Embryo tissues

Phenotypes

Phy. System:



increased grip strength	2 supporting datasets	Cbx5^{tm1a(EUCOMM)Wtsi}	homozygote	Early adult	2.85x10^-6
vertebral fusion	1 supporting dataset	Cbx5^{tm1a(EUCOMM)Wtsi}	homozygote	Early adult	2.57x10^-9
vertebral transformation	1 supporting dataset	Cbx5^{tm1a(EUCOMM)Wtsi}	homozygote	Early adult	1.56x10^-10
fusion of vertebral arches	1 supporting dataset	Cbx5^{tm1a(EUCOMM)Wtsi}	homozygote	Early adult	4.88x10^-8
decreased circulating glucose level	1 supporting dataset	Cbx5^{tm1a(EUCOMM)Wtsi}	homozygote	Early adult	6.23x10^-5

* Does not have a P-value assigned because it was manually marked as significant.

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* This parameter was manually assessed for significance.

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lacZ Expression

No adult expression data available for Cbx5.

Associated images

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Histopathology

There is no histopathology data found for Cbx5.

IMPC related publications

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External links

No external links available for Cbx5.

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*Cbx5^{em1(IMPC)Ccpcz}*	Exon Deletion	‌	mouse
*Cbx5^{tm1(KOMP)Vlcg}*	Reporter-tagged deletion allele (with selection cassette)	‌	ES Cell
*Cbx5^{tm1a(EUCOMM)Wtsi}*	KO first allele (reporter-tagged insertion with conditional potential)	‌	targeting vector ES Cell mouse
*Cbx5^{tm1e(EUCOMM)Wtsi}*	Targeted, non-conditional allele	‌	ES Cell

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