Adamts1 | ADAM metallopeptidase with thrombospondin type 1 motif 1
Physiological systems
22 / 24 physiological systems tested
10 Significantly impacted by the knock-out
Immune system Embryo Growth/size/body region Limbs/digits/tail Vision/eye Hematopoietic system Behavior/neurological Mortality/aging Cardiovascular system Renal/urinary system
12 No significant impact
2 Not tested
Data collections
Gene metrics:13Significant phenotypes
0Associated diseases
Expression examined in:0Adult tissues
0Embryo tissues
| abnormal spleen morphology | 1 supporting dataset | Adamts1em1(IMPC)Mbp | heterozygote | Early adult | N/A * | ||
| small kidney | 1 supporting dataset | Adamts1em1(IMPC)Mbp | heterozygote | Early adult | N/A * | ||
| abnormal placenta vasculature | 1 supporting dataset | Adamts1em1(IMPC)Mbp | homozygote | E18.5 | N/A * | ||
| preweaning lethality, incomplete penetrance | 3 supporting datasets | Adamts1em1(IMPC)Mbp | homozygote | Early adult | N/A * | ||
| no spontaneous movement | 1 supporting dataset | Adamts1em1(IMPC)Mbp | heterozygote | E18.5 | N/A * | ||
| abnormal body wall morphology | 1 supporting dataset | Adamts1em1(IMPC)Mbp | homozygote | E18.5 | N/A * | ||
| abnormal kidney morphology | 1 supporting dataset | Adamts1em1(IMPC)Mbp | heterozygote | Early adult | N/A * | ||
| no spontaneous movement | 1 supporting dataset | Adamts1em1(IMPC)Mbp | homozygote | E18.5 | N/A * | ||
| abnormal placenta morphology | 1 supporting dataset | Adamts1em1(IMPC)Mbp | homozygote | E18.5 | N/A * | ||
| eye hemorrhage | 1 supporting dataset | Adamts1em1(IMPC)Mbp | heterozygote | Early adult | 8.12x10-6 |
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External links
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| Adamts1em1(IMPC)Mbp | Exon Deletion | | mouse |