Fgf11 | fibroblast growth factor 11
Physiological systems
19 / 24 physiological systems tested
3 Significantly impacted by the knock-out
Digestive/alimentary Hematopoietic system Behavior/neurological
16 No significant impact
5 Not tested
Data collections
Viability data
Body weight measurements
Embryo imaging data
Body weight measurements
Embryo imaging data
Gene metrics:4Significant phenotypes
0Associated diseases
Expression examined in:0Adult tissues
0Embryo tissues
| abnormal startle reflex | 1 supporting dataset | Fgf11tm1a(EUCOMM)Wtsi | homozygote | Early adult | 3.63x10-5 | ||
| abnormal response to tactile stimuli | 1 supporting dataset | Fgf11tm1a(EUCOMM)Wtsi | homozygote | Early adult | 8.66x10-5 | ||
| increased mean corpuscular volume | 1 supporting dataset | Fgf11tm1a(EUCOMM)Wtsi | homozygote | Early adult | 6.74x10-6 | ||
| abnormal defecation | 1 supporting dataset | Fgf11tm1a(EUCOMM)Wtsi | homozygote | Early adult | 3.14x10-5 |
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Human diseases caused by Fgf11 mutations
The analysis uses data from IMPC, along with published data on other mouse mutants, in comparison to human disease reports in OMIM, Orphanet, and DECIPHER.
Phenotype comparisons summarize the similarity of mouse phenotypes with human disease phenotypes.
External links
No external links available for Fgf11.
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| Fgf11tm1(KOMP)Vlcg | Reporter-tagged deletion allele (with selection cassette) | | ES Cell |
| Fgf11tm1a(EUCOMM)Wtsi | KO first allele (reporter-tagged insertion with conditional potential) | | targeting vector ES Cell mouse |