Rgs4 | regulator of G-protein signaling 4

GeneMGI:108409Synonyms: ESTM48, ESTM50

Physiological systems

19 / 24 physiological systems tested

3 Significantly impacted by the knock-out

 Immune system Growth/size/body region Hematopoietic system

16 No significant impact

5 Not tested

Data collections

LacZ expression
Histopathology
Images
How IMPC generates data
Gene metrics:4Significant phenotypes
0Associated diseases
Expression examined in:0Adult tissues
0Embryo tissues

Phenotypes

increased eosinophil cell number2 supporting datasetsRgs4em1(IMPC)HhomozygoteLate adult4.15x10-29 
increased mean corpuscular volume1 supporting datasetRgs4em1(IMPC)HhomozygoteLate adult6.26x10-10 
decreased lymphocyte cell number1 supporting datasetRgs4em1(IMPC)HhomozygoteLate adult1.41x10-16 
increased spleen weight1 supporting datasetRgs4em1(IMPC)HhomozygoteLate adult3.15x10-5 
* Does not have a P-value assigned because it was manually marked as significant.
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* This parameter was manually assessed for significance.
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lacZ Expression

Associated images

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Histopathology

IMPC related publications

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Rgs4em1(IMPC)HExon Deletionmouse
Rgs4tm40813(L1L2_gt2)KO first allele (reporter-tagged insertion with conditional potential)targeting vector

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