Wnt10b | wingless-type MMTV integration site family, member 10B

GeneMGI:108061Synonyms: Wnt12

Physiological systems

22 / 24 physiological systems tested

3 Significantly impacted by the knock-out

Digestive/alimentary Nervous system Skeleton

19 No significant impact

2 Not tested

Data collections

LacZ expression
Histopathology
Images
How IMPC generates data

Viability data
Body weight measurements
Embryo imaging data

Allele products available

Gene metrics:5Significant phenotypes

4Associated diseases

Expression examined in:73Adult tissues

0Embryo tissues

Phenotypes

Phy. System:



abnormal brain morphology	1 supporting dataset	Wnt10b^{tm1e.1(KOMP)Wtsi}	homozygote	Early adult	N/A ^*
decreased bone mineral density	1 supporting dataset	Wnt10b^{tm1e.1(KOMP)Wtsi}	homozygote	Early adult	6.16x10^-8
abnormal cecum morphology	2 supporting datasets	Wnt10b^{tm1e.1(KOMP)Wtsi}	homozygote	Early adult	N/A ^*
hydrocephaly	1 supporting dataset	Wnt10b^{tm1e.1(KOMP)Wtsi}	homozygote	Early adult	N/A ^*
decreased bone mineral content	2 supporting datasets	Wnt10b^{tm1e.1(KOMP)Wtsi}	homozygote	Early adult	3.76x10^-6

* Does not have a P-value assigned because it was manually marked as significant.

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* This parameter was manually assessed for significance.

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lacZ Expression

No adult expression data available for Wnt10b.

Associated images

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Histopathology

There is no histopathology data found for Wnt10b.

IMPC related publications

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External links

No external links available for Wnt10b.

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*Wnt10b^{tm1a(KOMP)Wtsi}*	KO first allele (reporter-tagged insertion with conditional potential)	‌	targeting vector ES Cell
*Wnt10b^{tm1e(KOMP)Wtsi}*	Targeted, non-conditional allele	‌	ES Cell mouse
*Wnt10b^{tm1e.1(KOMP)Wtsi}*	Promoter excision from Targeted, non-conditional allele	‌	mouse

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