Ptprv | protein tyrosine phosphatase receptor type V
Physiological systems
17 / 24 physiological systems tested
2 Significantly impacted by the knock-out
Homeostasis/metabolism Nervous system
15 No significant impact
7 Not tested
Data collections
Gene metrics:2Significant phenotypes
0Associated diseases
Expression examined in:0Adult tissues
0Embryo tissues
| decreased circulating potassium level | 1 supporting dataset | Ptprvtm1b(NCOM)Mfgc | homozygote | Early adult | 2.45x10-5 | ||
| decreased prepulse inhibition | 1 supporting dataset | Ptprvtm1b(NCOM)Mfgc | homozygote | Early adult | 2.11x10-5 |
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Human diseases caused by Ptprv mutations
The analysis uses data from IMPC, along with published data on other mouse mutants, in comparison to human disease reports in OMIM, Orphanet, and DECIPHER.
Phenotype comparisons summarize the similarity of mouse phenotypes with human disease phenotypes.
This gene doesn't have any significant Histopathology hits. Click here to see the raw data
External links
No external links available for Ptprv.
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| Ptprvtm1a(NCOM)Mfgc | KO first allele (reporter-tagged insertion with conditional potential) | | targeting vector ES Cell mouse |
| Ptprvtm1b(NCOM)Mfgc | Reporter-tagged deletion allele (with selection cassette) | | mouse |